Results 191 to 200 of about 1,500,690 (354)

An efficient protocol for in vitro propagation of Fig (Ficus carica sp) and evaluation of genetic fidelity using RAPD and ISSR markers [PDF]

, 2016
Eldessoky S. Dessoky, Attia Attia, El-Awady Mohamed   +2 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Plasmodium falciparum histidine rich protein 2 (pfhrp2): an additional genetic marker suitable for anti-malarial drug efficacy trials. [PDF]

Malar J, 2022
Atroosh WM, Lau YL, Snounou G, Azzani M, Al-Mekhlafi HM.   +4 more
europepmc   +1 more source

Generation of a Polymorphic Marker Linked to Thymoma Susceptibility Gene of Rat 1 by Genetically-Directed Representational Difference Analysis.

, 2000
Kyoko Higo, Toshikazu Ushijima, Atsushi Oyabu, Chunlin Ye, Shigeru YAGYU, Hisahide Takahashi, Mutsushi Matsuyama   +6 more
openalex   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Lifetime expression of egg rejection behaviour in Eurasian magpies is associated with variation in a polymorphic genetic marker. [PDF]

Sci Rep
Molina-Morales M, Avilés JM, Precioso M, Martínez JG, Morales MM.   +4 more
europepmc   +1 more source

Genetic predisposition markers for prostate cancer

, 2015
Maria D Kanaeva, I. E. Orobtsova
openalex   +2 more sources

Morphological description, genetic diversity and population structure of safflower (Carthamus tinctoriusL.) mini core collection using SRAP and SSR markers [PDF]

, 2020
Seyed Mohammad Reza Hassani, Reza Talebi, Sayyed Saeid Pourdad, Amir Mohammad Naji, Farzad Fayaz   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

SoMarker: a genetic marker searching tool for Caenorhabditis elegans. [PDF]

G3 (Bethesda)
Dai CY, Zhang H, Zuryn S.
europepmc   +1 more source