Results 261 to 270 of about 1,474,286 (302)
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Journal of the American College of Surgeons, 2001
Sepsis is a systemic response to severe infection. Clinical sepsis is defined as an infection-induced syndrome including at least two of the features of systemic inflammatory response syndrome: fever or hypothermia (oral temperature .38°C or ,36°C); leukocytosis (.12,000 WBC/mm) or leukopenia (,4,000 WBC/ mm); tachycardia (heart rate .90 beats/minute);
A R, Tabrizi +3 more
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Sepsis is a systemic response to severe infection. Clinical sepsis is defined as an infection-induced syndrome including at least two of the features of systemic inflammatory response syndrome: fever or hypothermia (oral temperature .38°C or ,36°C); leukocytosis (.12,000 WBC/mm) or leukopenia (,4,000 WBC/ mm); tachycardia (heart rate .90 beats/minute);
A R, Tabrizi +3 more
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The Lancet, 1984
Narcolepsy has long been known to have a hereditary familial basis. All of 37 patients with narcolepsy expressed the major histocompatibility complex antigen HLA DR2 compared with 21.5% of 200 normal controls. This finding confirms the genetic basis for the disease, and furthermore links it with the short arm of chromosome 6.
N, Langdon +4 more
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Narcolepsy has long been known to have a hereditary familial basis. All of 37 patients with narcolepsy expressed the major histocompatibility complex antigen HLA DR2 compared with 21.5% of 200 normal controls. This finding confirms the genetic basis for the disease, and furthermore links it with the short arm of chromosome 6.
N, Langdon +4 more
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Current Opinion in Biotechnology, 1991
Advances in our understanding of polymorphisms found in eukaryotic genomes and improved methods for studying genetic markers should facilitate genetic linkage mapping and other applications. Progress within the past year includes characterization of the types, frequencies, and properties of tandemly repeated sequences, methods for obtaining the DNA ...
A, Edwards, C T, Caskey
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Advances in our understanding of polymorphisms found in eukaryotic genomes and improved methods for studying genetic markers should facilitate genetic linkage mapping and other applications. Progress within the past year includes characterization of the types, frequencies, and properties of tandemly repeated sequences, methods for obtaining the DNA ...
A, Edwards, C T, Caskey
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Genetic Markers of Osteoarthritis
Current Rheumatology Reviews, 2010Osteoarthritis (OA) is a chronic arthropathy, in which cartilage loss, osteophyte formation, and subchondral bone sclerosis lead to pain, disability, and a reduction in quality of life. OA is a multifactorial disease and OA cases are affected by both genetics and environment to varying degrees.
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GENETIC MARKERS IN THYROID NEOPLASIA
Endocrinology and Metabolism Clinics of North America, 2001Cancer is a disease of genes. Detection of genetic abnormalities associated with cancers of various cell types can now be used for genetic counseling, diagnosis or treatment selection. In the case of thyroid cancer, genetic testing for mutations of the RET oncogene has had a profound effect on the management of medullary thyroid carcinomas.
PUXEDDU, Efisio, Fagin J. A.
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Amyotrophic Lateral Sclerosis, 2000
As a result of the advances made in the field of molecular and population genetics, it is anticipated that several genes underlying ALS or predisposing to ALS might be identified in the near future. This will enable physicians to establish a diagnosis of ALS based on molecular findings in addition to clinical and electrophysiological findings.
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As a result of the advances made in the field of molecular and population genetics, it is anticipated that several genes underlying ALS or predisposing to ALS might be identified in the near future. This will enable physicians to establish a diagnosis of ALS based on molecular findings in addition to clinical and electrophysiological findings.
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Genetic markers of vasovagal syncope
Autonomic Neuroscience, 2021Vasovagal syncope may have a genetic predisposition. It has a high prevalence in some families, and children of a fainting parent are more likely to faint than those without a parent who faints. Having two fainting parents or a fainting twin increases the likelihood even further. Several genotypes appear to associate with the phenotype of positive tilt
Robert S, Sheldon, Brenda, Gerull
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Genetic Markers and Alcoholism
1983Genetic markers are genetically determined characteristics that have been found to occur in association with some common disorders. In alcoholism, four types of genetic markers have been studied to determine their frequency compared with the general population frequency.
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Beyond genetic markers: hypertension genes
Journal of Hypertension, 1994The dissection of the molecular genetics of hypertension is both a complex multidisciplinary challenge and a medical imperative. The Identification of hypertension genes will allow the dissection of etiologic mechanisms: the primary gene dysfunctions, gene interaction, and gene and environmental factor interaction, thus unravelling the heterogeneous ...
V L, Herrera, N, Ruiz-Opazo
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Genetic markers in methotrexate treatments
The Pharmacogenomics Journal, 2018Methotrexate (MTX), a structural analog of folic acid, is widely employed in the treatment of different cancers and autoimmune diseases. Despite the successful results observed, the main disadvantage lies in interpatient variability in the pharmacokinetic and pharmacodynamic parameters.
Andrea Giletti, Patricia Esperon
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