Results 1 to 10 of about 2,938,774 (308)
Genetic Predisposition to Neuroblastoma [PDF]
Children, 2018 Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis.
Erin K. Barr, Mark A. Applebaum
doaj +5 more sources
Principles of genetic predisposition to malignancies [PDF]
Hereditary Cancer in Clinical Practice, 2008 It is estimated that around 30% of all malignancies are caused by a "high-risk" genetic predisposition [1]. This estimation is based on an evaluation of occurrence of disease among monozygotic twins. If one of them is affected with prostate (PC) or breast cancer (BC), then the probability of occurrence of this disease in the second sibling is 40% for ...
Dębniak Tadeusz, Lubiński Jan
doaj +8 more sources
Greenness, Genetic Predisposition, and Tinnitus [PDF]
Advanced ScienceThis study aimed to investigate the association between residential greenness and tinnitus and the potential interaction between greenness and genetic predisposition to tinnitus.
Lan‐Lai Yuan +3 more
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Genetic predisposition for Type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis. [PDF]
PLoS ONE, 2011 BACKGROUND: Development of Type 2 diabetes, like obesity, is promoted by a genetic predisposition. Although several genetic variants have been identified they only account for a small proportion of risk.
Peter Arner +3 more
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Genetic Predisposition to Hepatocellular Carcinoma
Metabolites, 2022 Liver preneoplastic and neoplastic lesions of the genetically susceptible F344 and resistant BN rats cluster, respectively, with human HCC with better (HCCB) and poorer prognosis (HCCP); therefore, they represent a valid model to study the molecular ...
Rosa M. Pascale +3 more
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Genetic Predisposition to Solid Pediatric Cancers
Frontiers in Oncology, 2020 Progresses over the past years have extensively improved our capacity to use genome-scale analyses—including high-density genotyping and exome and genome sequencing—to identify the genetic basis of pediatric tumors.
Mario Capasso +10 more
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Genetic Predisposition to Cancer [PDF]
British Journal of Cancer, 2006 The US Surgeon General's ‘Family History Initiative', launched in 2004, underlines increasing public and professional awareness of the importance of knowing the health history of your close relatives and the benefits this can bring to the health care of family members.
Eisinger, F
core +4 more sources
Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children’s Oncology Group AREN18B5-Q [PDF]
Nature Communications, 2023 Developing synchronous bilateral Wilms tumor suggests an underlying (epi)genetic predisposition. Here, we evaluate this predisposition in 68 patients using whole exome or genome sequencing (n = 85 tumors from 61 patients with matched germline blood DNA),
Andrew J. Murphy +33 more
doaj +3 more sources
Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program. [PDF]
Scientific Reports, 2019 Both genetic and lifestyle factors contribute to an individual\u27s disease risk, suggesting a multi-omic approach is essential for personalized prevention.
Conomos, Matthew P +7 more
core +3 more sources
Privacy-Preserving Genetic Relatedness Test [PDF]
arXiv, 2016 An increasing number of individuals are turning to Direct-To-Consumer (DTC) genetic testing to learn about their predisposition to diseases, traits, and/or ancestry. DTC companies like 23andme and Ancestry.com have started to offer popular and affordable ancestry and genealogy tests, with services allowing users to find unknown relatives and long ...
De Cristofaro, Emiliano +2 more
arxiv +4 more sources