Results 1 to 10 of about 364,926 (322)

Greenness, Genetic Predisposition, and Tinnitus [PDF]

Advanced Science
This study aimed to investigate the association between residential greenness and tinnitus and the potential interaction between greenness and genetic predisposition to tinnitus.
Lan‐Lai Yuan, Dan‐Kang Li, Yao‐Hua Tian, Yu Sun   +3 more
doaj   +4 more sources

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities [PDF]

Nature Communications
Type 2 diabetes is associated with a range of non-cardiovascular non-oncologic comorbidities. To move beyond associations and evaluate causal effects between type 2 diabetes genetic predisposition and 21 comorbidities, we apply Mendelian randomization ...
Ana Luiza Arruda, Ozvan Bocher, Henry J. Taylor, Davis Cammann, Satoshi Yoshiji, Xianyong Yin, Chi Zhao, Jingchun Chen, Alexis C. Wood, Ken Suzuki, Josep M. Mercader, Cassandra N. Spracklen, James B. Meigs, Marijana Vujkovic, George Davey Smith, Jerome I. Rotter, Benjamin F. Voight, Andrew P. Morris, Eleftheria Zeggini   +18 more
doaj   +2 more sources

Genetic Predisposition to Hepatocellular Carcinoma

Metabolites, 2022
Liver preneoplastic and neoplastic lesions of the genetically susceptible F344 and resistant BN rats cluster, respectively, with human HCC with better (HCCB) and poorer prognosis (HCCP); therefore, they represent a valid model to study the molecular ...
Rosa M. Pascale, Diego F. Calvisi, Francesco Feo, Maria M. Simile   +3 more
doaj   +3 more sources

Genetic predisposition in sarcomas: clinical implications and management [PDF]

EClinicalMedicine
Summary: Recent studies indicate up to 20% of sarcomas may be associated with predisposition genes, and this number will probably increase as genetic testing becomes more available.
Elizabeth A. Connolly, Kjetil Boye, Sylvie Bonvalot, Christian P. Kratz, Andreas Leithner, David Malkin, Christina Messiou, Aisha B. Miah, Pan Pantziarka, Beate Timmermann, Winette T.A. van der Graaf, David M. Thomas, Silvia Stacchiotti   +12 more
doaj   +2 more sources

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK Biobank [PDF]

Journal of Sport and Health Science
Background: It is unclear whether physical activity can benefit participants with high genetic predisposition to cardiovascular disease. We examined the joint associations of intensity-specific physical activity and genetic predisposition (based on ...
Matthew N. Ahmadi, Hamish D. Mundell, Greg T. Sutherland, Mark Hamer, Elina Sillanpää, Joanna M. Blodgett, Borja del Pozo Cruz, Emmanuel Stamatakis   +7 more
doaj   +2 more sources

Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism [PDF]

Heliyon
Background: Several studies suggested the genetic association between IL10RA variants and susceptibility to Behcet's disease (BD). However, the precise mechanism of the association is still unknown.
Handan Tan, Zhenyu Zhong, Xiaojie Feng, Xiang Luo, Qingfeng Cao, Peizeng Yang   +5 more
doaj   +2 more sources

Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing. [PDF]

PLoS ONE, 2017
Genetic predisposition increases the risk of familial breast cancer. Recent studies indicate that genetic predisposition for familial breast cancer can be ethnic-specific.
Yeong C Kim, Amr S Soliman, Jian Cui, Mohamed Ramadan, Ahmed Hablas, Mohamed Abouelhoda, Nehal Hussien, Ola Ahmed, Abdel-Rahman Nabawy Zekri, Ibrahim A Seifeldin, San Ming Wang   +10 more
doaj   +1 more source

Genetic predisposition for Type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis. [PDF]

PLoS ONE, 2011
BACKGROUND: Development of Type 2 diabetes, like obesity, is promoted by a genetic predisposition. Although several genetic variants have been identified they only account for a small proportion of risk.
Peter Arner, Erik Arner, Ann Hammarstedt, Ulf Smith   +3 more
doaj   +1 more source

Lessons From Pediatric MDS: Approaches to Germline Predisposition to Hematologic Malignancies

Frontiers in Oncology, 2022
Pediatric myelodysplastic syndromes (MDS) often raise concern for an underlying germline predisposition to hematologic malignancies, referred to as germline predisposition herein.
Serine Avagyan, Akiko Shimamura
doaj   +1 more source

Modifier genes and Lynch syndrome: some considerations

Hereditary Cancer in Clinical Practice, 2022
Lynch Syndrome (LS) is a highly variable entity with some patients presenting at very young ages with malignancy whereas others may never develop a malignancy yet carry an unequivocal genetic predisposition to disease.
Rodney J. Scott
doaj   +1 more source