HLA class II associations with rheumatic heart disease among clinically homogeneous patients in children in Latvia [PDF]
Genetic control of immune reactions has a major role in the development of rheumatic heart disease (RHD) and differs between patients with rheumatic fever (RF).
Eglite, Jelena+5 more
core +2 more sources
Mode‐dependent Far‐field Radiation of Circularly Polarized Light by a Single Plasmonic Nanohelix
The numerical simulations explored the chiroptical response and far‐field radiation behaviors of single plasmonic nanoantennas transitioning into helical structures. This study highlights the ability of these plasmonic nanohelices to regulate the far‐field directionality of radiation power and circular polarization in plasmon‐exciton coupled systems ...
Yiou Cui+10 more
wiley +1 more source
Patient Attitudes Toward Genetic Testing for Inherited Predispositions to Hematologic Malignancies [PDF]
Although inherited predispositions to hematologic malignancies have previously been considered extremely rare, approximately 12 causative genes have been implicated in the last decade.
Beecroft, Taylor
core +1 more source
Clinicopathological characteristics of histiocytic sarcoma affecting the central nervous system in dogs. [PDF]
BackgroundHistiocytic sarcoma affecting the central nervous system (CNS HS) in dogs may present as primary or disseminated disease, often characterized by inflammation.
Crowe, Chelsea M+10 more
core
Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]
Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS+7 more
core +1 more source
Advances and Outlook of Nickel‐Based MOFs–LDHs Materials for Energy Conversion
In this graphical abstract, we present the pivotal gap between the activity and stability parameters as far as intergrated Ni‐based MOF/LDF electrocatalysts are concerned. For large scale application, these two parameters should be optimized and furthermore balanced in order to promote sustainable electrocatalytic hydrogen production.
Lincoln Einstein Kengne Fotso+4 more
wiley +1 more source
On Sin, Repentance, Christian Nurture, And The Genetics of Personality [PDF]
Dean Homer\'s description of the genetics of personality includes two components: temperament and character. Temperament is a product of the interaction of the individual\'s genes with early stimuli, whereas character is formed by parenting, social ...
Keefer, Robert A.
core +1 more source
Sleep characteristics modify the association between genetic predisposition to obesity and anthropometric measurements in 119,679 UK Biobank participants [PDF]
Background - Obesity is a multifactorial condition influenced by genetics, lifestyle and environment. Objective - To investigate whether the association between a validated genetic profile risk score for obesity (GPRS-obesity) with body mass index (BMI)
Bailey, Mark E.S.+10 more
core +1 more source
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng+7 more
wiley +1 more source
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He+16 more
wiley +1 more source