Results 121 to 130 of about 214,782 (285)

Rooted in Risk: Genetic Predisposition for Low-Density Lipoprotein Cholesterol Level Associates with Diminished Low-Density Lipoprotein Cholesterol Response to Statin Treatment

, 2016
Roelof A. J. Smit, Iris Postmus, Stella Trompet, Michael R. Barnes, Helen R. Warren, Benoît J. Arsenault, Daniel I. Chasman, L. Adrienne Cupples, G. A. Hitman, Ronald M. Krauss, Xiaohui Li, Bruce M. Psaty, Charles Stein, Jerome I. Rotter, J. Wouter Jukema   +14 more
openalex   +2 more sources

Association of HLA DRB variants to genetic predisposition to rheumatoid arthritis [PDF]

, 2014
Bushra Jarullah
openalex   +1 more source

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

Genetic predisposition [PDF]

, 2019
openaire   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source

Genetic predisposition to cancer [PDF]

British Journal of Cancer, 1991
openaire   +2 more sources

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not

, 2017
Monica Aas, Ingrid Melle, Francesco Bettella, Srdjan Djurovic, Stéphanie Le Hellard, Thomas Bjella, Petter Andreas Ringen, Trine Vik Lagerberg, Olav B. Smeland, Ingrid Agartz, Ole A. Andreassen, Martin Tesli   +11 more
openalex   +2 more sources

Supplementary Table 1 from Sleep Behaviors, Genetic Predispositions, and Risk of Esophageal Cancer

, 2023
Xiaoyan Wang, Ruiyi Tian, Xiaoyu Zong, Myung Sik Jeon, Jingqin Luo, Graham A. Colditz, Jean S. Wang, Konstantinos K. Tsilidis, Yo‐El S. Ju, Ramaswamy Govindan, Varun Puri, Yin Cao   +11 more
openalex   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source