Results 131 to 140 of about 214,782 (285)

Principles of genetic predisposition to malignancies

Hereditary Cancer in Clinical Practice, 2008
Dębniak Tadeusz, Lubiński Jan
doaj   +1 more source

Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia

, 2018
Michelle L. Churchman, Maoxiang Qian, Geertruy te Kronnie, Ranran Zhang, Wenjian Yang, Hui Zhang, Tobia Lana, Paige Tedrick, Rebekah Baskin, Katherine Verbist, Jennifer L. Peters, Meenakshi Devidas, Elizabeth A. Raetz, Eric Larsen, Paul L. Martin, W. Paul Bowman, Naomi Winick, Elaine R. Mardis, Robert S. Fulton, Martin Stanulla, William E. Evans, Mary V. Relling, Ching‐Hon Pui, Stephen P. Hunger, Mignon L. Loh, Rupert Handgretinger, Kim E. Nichols, Charles G. Mullighan, Jun J. Yang   +28 more
openalex   +1 more source

Visualizing Strain‐Coupled Cryogenic Phase Transitions and Defect Dynamics in Perovskite Quantum Dots Using In Situ STEM

Advanced Science, EarlyView.
Cryogenic cooling induces an orthorhombic‐to‐monoclinic phase transition in CsPbBr3 quantum dots, accompanied by pronounced strain localization at surfaces and interfaces. Multimodal in situ STEM directly visualize reversible defect healing during moderate cryogenic treatment and irreversible degradation upon prolonged exposure, revealing the intrinsic
Xinjuan Li, Zhao Jiang, Si Chen, Yi Tang, Bofeng Xue, Tianhao Wu, Yang Lu, Xavier Moya, Akshay Rao, Zhongzheng Yu, Caterina Ducati   +10 more
wiley   +1 more source

Association of genetic predisposition to dyslipidemia and physical activity with incident dementia. [PDF]

Alzheimers Dement
Liang Y, Xie S, Sheng D, Ding L, Yang T, Jia J.   +5 more
europepmc   +1 more source

Genetic predisposition, Western dietary pattern, and the risk of type 2 diabetes in men

, 2009
Lu Qi, Marilyn C. Cornelis, Cuilin Zhang, Rob M. van Dam, Frank B. Hu   +4 more
openalex   +2 more sources

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Genetic predisposition to persistent fatigue after a diagnosis of colorectal cancer. [PDF]

J Natl Cancer Inst
Kazemian E, Mo Q, Matejcic M, Tsai YY, Sobieski D, Li X, Hoogland AI, Crowder SL, Gonzalez BD, Oswald LB, Sleight AG, Nguyen N, Loroña NC, Damerell V, Komrokji KR, Mooney K, Playdon MC, Ulrich CM, Li CI, Shibata D, Toriola AT, Ose J, Peoples AR, Hardikar S, Kahlert C, Siegel EM, Bower JE, Schmit SL, Gigic B, Jim HSL, Figueiredo JC.   +30 more
europepmc   +1 more source

Is There A Genetic Predisposition for Transitional Cell Carcinoma of the Bladder at a Young Age?

, 2023
Selim Taş, Ali Erhan Eren, Mahmut Taha Ölçücü, Barış Paksoy, Ekrem İslamoğlu, Mehmet Boğa   +5 more
openalex   +2 more sources

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source