Results 141 to 150 of about 214,782 (285)

Genetic Predisposition in Müllerian Malformations: A Case Report. [PDF]

Cureus
Rendón-Molina A, Olguín-Ortega A.
europepmc   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

Insights into the Pathophysiology of Scheuermann's Kyphosis: From Structural Deformities to Genetic Predisposition and Underlying Signalling Pathways. [PDF]

Biomolecules
Kaspiris A, Spyrou I, Marougklianis V, Afrati SR, Sakellariou E, Varsamos I, Karampinas P, Vasiliadis E, Pneumaticos SG.   +8 more
europepmc   +1 more source

Genetic predisposition to breast and ovarian cancer [PDF]

, 2017
Pierre O. Chappuis, B. Bolliger, Nicole Bürki, K. Buser, Karl Heinimann, Christian Monnerat, Rudolf Morant, Olivia Pagani, Lucien Perey, Manuela Rabaglio, Sheila Unger, on behalf of the Swiss Group for Clinical Cancer Research Network for Cancer Predisposition Testing and Counseling   +11 more
openalex   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Whole genome sequencing-based analysis of genetic predisposition to adult glioblastoma. [PDF]

NPJ Genom Med
van Opijnen MP, van Valkengoed DR, de Ligt J, de Vos FYF, Broekman MLD, Cuppen E, Koster R.   +6 more
europepmc   +1 more source

Associations of dietary cholesterol consumption with incident diabetes and cardiovascular disease: the role of genetic variability in cholesterol absorption and disease predisposition

Shuxiao Shi, Ying Dong, Sujing Wang, Xihao Du, Nannan Feng, Lan Xu, Victor W. Zhong   +6 more
openalex   +1 more source

Genetic Predisposition to the Development of Acute Community-Acquired Pneumonia

, 2010
L. Ye. Salnikova, T. V. Smelaya, В. В. Мороз, А. М. Голубев, Н. Ш. Лаптева, G. G. Poroshenko, А. В. Рубанович   +6 more
openalex   +2 more sources

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

On the Heritability of Choice, Judgment, and "Irrationality": Genetic Effects on Prudence and Constructive Predispositions

, 2009
Itamar Simonson, Aner Sela
openalex   +1 more source