Results 181 to 190 of about 364,926 (322)

Self‐Assembled Dictamni Cortex Nanoparticles Ameliorate Psoriasis by Epigenetic Modulation of HSP90AB1 and Suppression of the Inflammatory Response

open access: yesAdvanced Science, EarlyView.
This study develops self‐assembled Dictamni Cortex (BXP)‐Fe(III) infinite coordination polymer nanoparticles (NB) to improve BXP's solubility and bioavailability for psoriasis. NB transdermally treats psoriasis by targeting the epigenetic regulator CTCF (CCCTC‐binding factor), suppressing HSP90AB1 (heat shock protein 90 alpha family class B member 1 ...
Zhengyi Zhang   +15 more
wiley   +1 more source

Comprehensive Screening for Early Cancer Detection in Individuals With Genetic Predisposition. [PDF]

open access: yesJCO Precis Oncol
Bodunova NA   +8 more
europepmc   +1 more source

Dual‐Pedicle Tissue‐Engineered Trachea Promotes Biomimetic Cartilaginous Framework, Vascularization, and Epithelial Lining for Long‐Segment Tracheal Reconstruction

open access: yesAdvanced Science, EarlyView.
Overcoming the limitations of conventional grafts, a biomimetic trachea with two independent vascular pedicles enables rapid integration and sustained patency. This approach markedly improves survival rates, restores the epithelial barrier, and promotes regenerative pathways, presenting a transformative paradigm for clinical application.
Ziming Wang   +9 more
wiley   +1 more source

Gene expression profile of normal lungs predicts genetic predisposition to lung cancer in mice [PDF]

open access: bronze, 2003
Manuela Gariboldi   +8 more
openalex   +1 more source

Body Mass Index as a Potential Mediator of the Association Between Gout and Hypertension Among Chinese Older Adults: A Mediation Analysis in a Cross‐Sectional Study

open access: yesAGING MEDICINE, EarlyView.
This study employed mediation analysis and found that BMI played a significant mediating role in the relationship between gout and hypertension. The mediating effect accounted for 12.59% of the total effect (ACME = 0.0244). ACME, average causal mediation effect.
Jia Wang   +9 more
wiley   +1 more source

Molecular Analyses in Diagnosis of High Genetic Predispositions to Malignancies.

open access: bronze, 2000
Jan Lubiński   +14 more
openalex   +2 more sources

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