Results 11 to 20 of about 2,961,248 (406)

Genetic Predisposition to Neuroblastoma [PDF]

Children, 2018
Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis.
Erin K. Barr, Mark A. Applebaum
doaj   +5 more sources

Greenness, Genetic Predisposition, and Tinnitus. [PDF]

Adv Sci (Weinh)
This study aimed to investigate the association between residential greenness and tinnitus and the potential interaction between greenness and genetic predisposition to tinnitus.
Yuan LL, Li DK, Tian YH, Sun Y.
europepmc   +4 more sources

Genetic predisposition for Type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis. [PDF]

PLoS ONE, 2011
BACKGROUND: Development of Type 2 diabetes, like obesity, is promoted by a genetic predisposition. Although several genetic variants have been identified they only account for a small proportion of risk.
Peter Arner, Erik Arner, Ann Hammarstedt, Ulf Smith   +3 more
doaj   +5 more sources

Genetic Predisposition to Hepatocellular Carcinoma

Metabolites, 2022
Liver preneoplastic and neoplastic lesions of the genetically susceptible F344 and resistant BN rats cluster, respectively, with human HCC with better (HCCB) and poorer prognosis (HCCP); therefore, they represent a valid model to study the molecular ...
Rosa M. Pascale, Diego F. Calvisi, Francesco Feo, Maria M. Simile   +3 more
doaj   +3 more sources

Genetic predisposition in sarcomas: clinical implications and management. [PDF]

EClinicalMedicine
Summary: Recent studies indicate up to 20% of sarcomas may be associated with predisposition genes, and this number will probably increase as genetic testing becomes more available.
Connolly EA, Boye K, Bonvalot S, Kratz CP, Leithner A, Malkin D, Messiou C, Miah AB, Pantziarka P, Timmermann B, van der Graaf WTA, Thomas DM, Stacchiotti S.   +12 more
europepmc   +2 more sources

Genetic Predisposition to Solid Pediatric Cancers

Frontiers in Oncology, 2020
Progresses over the past years have extensively improved our capacity to use genome-scale analyses—including high-density genotyping and exome and genome sequencing—to identify the genetic basis of pediatric tumors.
Mario Capasso, Mario Capasso, Annalaura Montella, Matilde Tirelli, Matilde Tirelli, Teresa Maiorino, Teresa Maiorino, Sueva Cantalupo, Sueva Cantalupo, Achille Iolascon, Achille Iolascon   +10 more
doaj   +2 more sources

Principles of genetic predisposition to malignancies [PDF]

Hereditary Cancer in Clinical Practice, 2008
It is estimated that around 30% of all malignancies are caused by a "high-risk" genetic predisposition [1]. This estimation is based on an evaluation of occurrence of disease among monozygotic twins. If one of them is affected with prostate (PC) or breast cancer (BC), then the probability of occurrence of this disease in the second sibling is 40% for ...
Dębniak Tadeusz, Lubiński Jan
doaj   +4 more sources

Genetic Predisposition to Cancer [PDF]

British Journal of Cancer, 2006
The US Surgeon General's ‘Family History Initiative', launched in 2004, underlines increasing public and professional awareness of the importance of knowing the health history of your close relatives and the benefits this can bring to the health care of family members.
Eisinger, F
core   +4 more sources

Privacy-Preserving Genetic Relatedness Test [PDF]

arXiv, 2016
An increasing number of individuals are turning to Direct-To-Consumer (DTC) genetic testing to learn about their predisposition to diseases, traits, and/or ancestry. DTC companies like 23andme and Ancestry.com have started to offer popular and affordable ancestry and genealogy tests, with services allowing users to find unknown relatives and long ...
De Cristofaro, Emiliano, Liang, Kaitai, Zhang, Yuruo   +2 more
arxiv   +4 more sources

Genetic predisposition to Behcet's disease mediated by a IL10RA enhancer polymorphism. [PDF]

Heliyon
Background: Several studies suggested the genetic association between IL10RA variants and susceptibility to Behcet's disease (BD). However, the precise mechanism of the association is still unknown.
Tan H, Zhong Z, Feng X, Luo X, Cao Q, Yang P.   +5 more
europepmc   +2 more sources