Results 11 to 20 of about 364,926 (322)

Genetic Predisposition to Neuroblastoma [PDF]

open access: yesChildren, 2018
Neuroblastoma is the most common solid tumor in children under the age of one. It displays remarkable phenotypic heterogeneity, resulting in differences in outcomes that correlate with clinical and biologic features at diagnosis.
Erin K. Barr, Mark A. Applebaum
doaj   +4 more sources

Principles of genetic predisposition to malignancies [PDF]

open access: yesHereditary Cancer in Clinical Practice, 2008
It is estimated that around 30% of all malignancies are caused by a "high-risk" genetic predisposition [1]. This estimation is based on an evaluation of occurrence of disease among monozygotic twins. If one of them is affected with prostate (PC) or breast cancer (BC), then the probability of occurrence of this disease in the second sibling is 40% for ...
Dębniak Tadeusz, Lubiński Jan
doaj   +4 more sources

Genetic predisposition to helminthiases [PDF]

open access: yesRussian Journal of Genetics: Applied Research, 2013
Helminthes accompany human beings from the early period of the formation, there is a long-term coevolution between parasite and human, helminthes represent a major selective force for human immune genes. Data on genetic control of the intensity and clinical traits of helminthinfection in different populations, including results obtained by whole-genome
Irina V. Saltykova   +3 more
openaire   +2 more sources

Genetic predisposition to cancer [PDF]

open access: yesClinical Medicine, 2005
Over recent decades a number of genes causing predisposition to cancer have been identified. Some of these cause rare autosomal dominant monogenic cancer predisposition syndromes. In the majority of families, the increased incidence of cancers is due to a multifactorial aetiology with a number of lower penetrance cancer predisposition genes interacting
Shirley Hodgson, Clare Turnbull
openaire   +3 more sources

Genetic predisposition for cervical cancer

open access: yesАкушерство, гинекология и репродукция, 2020
Aim: to assess a role of genetic factors and human papillomavirus (HPV) in developing cervical neoplasia based on analyzing current publications on virus-induced carcinogenesis.Materials and methods.
T. V. Rotaru   +2 more
doaj   +1 more source

Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis [PDF]

open access: yes, 2018
BACKGROUND: Dysfunction of the circadian clock and polymorphisms of some circadian genes have been linked to cancer development and progression. We investigated the relationship between circadian genes germline variation and susceptibility or prognosis ...
Benna, Clara   +6 more
core   +2 more sources

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

open access: yes, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D.   +7 more
core   +2 more sources

Androgenetic alopecia: a review [PDF]

open access: yes, 2017
Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma   +7 more
core   +1 more source

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