Results 191 to 200 of about 353,849 (343)

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

EVIDENCE FOR A GENETIC PREDISPOSITION TOWARDS ACUTE REJECTION AFTER KIDNEY AND SIMULTANEOUS KIDNEY-PANCREAS TRANSPLANTATION1

, 2000
Ronald P. Pelletier, Vera Pravica, Chris Perrey, Dongyuan Xia, Ronald M. Ferguson, Ian V. Hutchinson, Charles G. Orosz   +6 more
openalex   +1 more source

Genetic predisposition for productive life is associated with functional inactivation of a AP2-binding site in the promoter of the stress protein 70.1-encoding gene in cattle [PDF]

, 2003
M. Schwerin, Hanka Sanftleben, S. Grupe
openalex   +1 more source

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

Genetic Predisposition Toward Multicellularity in Chlamydomonas reinhardtii. [PDF]

Genome Biol Evol
Chen ICK, Khatri S, Herron MD, Rosenzweig F.   +3 more
europepmc   +1 more source

Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury

Animal Models and Experimental Medicine, EarlyView.
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin, Mathieu Magnin, Axel Aigle, Timothée Schuhler, Jean‐Yves Ayoub, Romain Lac, Charlotte Slek, Thomas Brichart, Abdessalem Hammed, Vanessa Louzier   +9 more
wiley   +1 more source

Frailty, genetic predisposition, and incident chronic kidney disease. [PDF]

Sci Rep
Zou S, Sun Y, Zhou Y, Yu B, Li J, Yu Y, Chen J, Li Y, Wang N, Wang L.   +9 more
europepmc   +1 more source

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

Animal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera, Abeer Abdullah Alghamdi, Mesfer Al‐Shahrani, Reem M. Al‐Gahtani, Bashayer Saad Alghamdi, Gaffar Sarwar Zaman, Mohammed Abdul Rasheed, Hassan Al‐Shehri, Lana Al‐qhtani, Syed Parween Ali, Umme Hani, Talha Bin Emran   +11 more
wiley   +1 more source

The Georgia Cardiovascular Twin Study: Influence of Genetic Predisposition and Chronic Stress on Risk for Cardiovascular Disease and Type 2 Diabetes [PDF]

, 2006
Dongliang Ge, Yanbin Dong, Xiaoling Wang, Frank A. Treiber, Harold Snieder   +4 more
openalex   +2 more sources

Dietary inflammatory potential, genetic predisposition, and incidence of Crohn's disease and ulcerative colitis. [PDF]

Nutr Metab (Lond)
Gu JM, Zhao M, Zhu J, Tao HW, Shao XP, Qin LQ, Ge YY, Chen GC.   +7 more
europepmc   +1 more source