Results 201 to 210 of about 353,849 (343)

Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use [PDF]

open access: bronze, 2004
Carmen Martínez   +7 more
openalex   +1 more source

Strategies for optimization of hypoglycemia rat models

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher   +4 more
wiley   +1 more source

Complex genetic predisposition in adult and juvenile rheumatoid arthritis. [PDF]

open access: gold, 2004
Bianca Miterski   +6 more
openalex   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling   +7 more
wiley   +1 more source

Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation [PDF]

open access: bronze, 2004
N. Julian H. Sturt   +7 more
openalex   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica   +4 more
wiley   +1 more source

A case of possible genetic predisposition to myelodysplastic syndrome [PDF]

open access: hybrid, 2004
Manoela Marques Ortega   +5 more
openalex   +1 more source

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