Results 211 to 220 of about 353,849 (343)

Midlife Steroid‐Binding Globulin Levels and In Vivo Neuroimaging Measures of Tau in Older Men and Women

Annals of Neurology, EarlyView.
Objective In men and women, sex steroid hormones have been associated with increased risk of Alzheimer's disease (AD) dementia. We aimed to investigate the influence of midlife testosterone and sex hormone binding globulin (SHBG) levels on later‐life in vivo markers of β‐amyloid (Aβ) and tau deposition in clinically healthy older men. Methods This time‐
Rachel F. Buckley, Matthew Scott, Emer R. McGrath, Gillian Coughlan, Mabel Seto, Saptaparni Ghosh, Heidi I. L. Jacobs, Claudia L. Satizabal, Emma Thibault, Vasan Ramachandran, Joanne M. Murabito, Reisa A. Sperling, Keith A. Johnson, Ravi Jasuja, Shalender Bhasin, Sudha Seshadri, Alexa S. Beiser   +16 more
wiley   +1 more source

The Interplay of Genetic Predisposition, Circadian Misalignment, and Metabolic Regulation in Obesity. [PDF]

Curr Obes Rep
Halder SK, Melkani GC.
europepmc   +1 more source

Genetic Mapping of a Third Li-Fraumeni Syndrome Predisposition Locus to Human Chromosome 1q23 [PDF]

, 2005
Linda L. Bachinski, Shodimu-Emmanuel Olufemi, Xiaojun Zhou, Chih‐Chieh Wu, Linwah Yip, Sanjay Shete, Guillermina Lozano, Christopher I. Amos, Louise C. Strong, Ralf Krahe   +9 more
openalex   +1 more source

Subthalamic Electrophysiological Mapping of Gait Initiation Dynamics and Freezing in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The objective of this study was to investigate the relationships among subthalamic nucleus (STN) activity, gait initiation (GI), and freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods We recorded GI and STN local field potentials (LFPs) via externalized cables in 38 patients with PD (35 reporting FOG in daily life ...
Antoine Collomb‐Clerc, Mathieu Yeche, Adèle Demain, Angèle Van Hamme, Claire Olivier, Hayat Belaid, Déborah Ziri, Stéphane Derrey, Sara Fernandez‐Vidal, Katia Lehongre, Carine Karachi, Brian Lau, Marie‐Laure Welter   +12 more
wiley   +1 more source

Genetic Predisposition to Latex Allergy [PDF]

, 2005
Robert H. Brown, Robert G. Hamilton, Margaret Mintz, Anne Jedlicka, Alan L. Scott, Steven R. Kleeberger   +5 more
openalex   +1 more source

Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective A better understanding of factors associated with multiple sclerosis (MS) disease activity and disability is needed. Given the strong link between comorbid depression and MS disease activity and disability, we aimed to determine whether the depression genetic burden, as modelled using its polygenic score, is associated with MS disease ...
Ali Manouchehrinia, Kathryn C. Fitzgerald, Amber Salter, Ruth Ann Marrie, Lars Alfredsson, Charles N. Bernstein, James M. Bolton, Gary Cutter, John D. Fisk, Lesley A. Graff, Carol A. Hitchon, Jan Hillert, Ingrid Kockum, Yi Lu, Fred D. Lublin, Kyla McKay, Tomas Olsson, Scott Patten, Amit Patki, Hayley Riel, Klementy Shchetynsky, Pernilla Stridh, Hemant K. Tiwari, Jerry S. Wolinsky, Kaarina Kowalec   +24 more
wiley   +1 more source

Genetic predisposition to adiposity, and type 2 diabetes: the role of lifestyle and phenotypic adiposity. [PDF]

Eur J Endocrinol
Zhang M, Ward J, Strawbridge RJ, Anderson JJ, Celis-Morales C, Pell JP, Ho FK, Lyall DM.   +7 more
europepmc   +1 more source

Hereditary cancer predisposition in children: Genetic basis and clinical implications [PDF]

, 2006
Brigitte Strahm, David Malkin
openalex   +1 more source

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

Advanced NanoBiomed Research, EarlyView.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman, Sungyeon Kang, Sangyong Jon   +2 more
wiley   +1 more source

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

Advanced NanoBiomed Research, EarlyView.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou, Tianyi Xia, Jiheng Xiao, Jianhui Xiang, Hanhong Fang, Haoran Zhou, Yiqiang Hu, Liming Xiong   +7 more
wiley   +1 more source