Results 271 to 280 of about 372,458 (325)

ROS‐induced modifications of fibrin clots connect immune responses to atherothrombosis in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. While oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

Genetic predisposition to childhood cancer.

World J Clin Pediatr
Roganovic J.
europepmc   +1 more source

Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Lifespan longitudinal changes in mesocortical thickness and executive function: Role of dopaminergic genetic predisposition

Giuseppe G. Miranda, Chen Gonen, Jessica N. Kraft, Karen M. Rodrigue, Kristen M. Kennedy   +4 more
openalex   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

Arthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Genetic predisposition to myelodysplastic syndrome: Genetic counseling and transplant implications. [PDF]

Semin Hematol
Liu Y, Calzone K, McReynolds LJ.
europepmc   +1 more source

Integrating Vascular Aging and Genetic Risk: The Combined Impact of Estimated Pulse Wave Velocity and Genetic Predisposition on Coronary Artery Disease

Chang Sheng, Rui Zhou, Hongcai Wang, Ling Jin, Guo‐Qiang Lin, Pu Yang, Wei Wang   +6 more
openalex   +1 more source

Genetic predisposition to longer lifespan, lifestyle factors, and all-cause mortality: a 17-year prospective cohort study

Tynkkynen NP, Joensuu L, Herranen P, Kaprio J, Törmäkangas T, Sillanpää E.   +5 more
europepmc   +1 more source

Genetic Predisposition to Benign Prostatic Hyperplasia: Where Do We Stand? [PDF]

Eur Urol Open Sci
Hennenberg M, Hu S, Tamalunas A, Stief CG.   +3 more
europepmc   +1 more source

National Mortality Databases to Assess Disease Burden in Systemic Autoimmune Diseases: A Valuable Resource, But with Limitations

Arthritis &Rheumatology, Accepted Article.
Disease‐specific mortality statistics are useful measures of disease burden. Population‐based studies from a few United States counties have reported mortality in systemic autoimmune diseases (SAID). However, due to substantial differences in the population structure of these counties as well as relatively small numbers of SAID deaths in these counties,
Ram Raj Singh
wiley   +1 more source