Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program. [PDF]
Scientific Reports, 2019 Both genetic and lifestyle factors contribute to an individual\u27s disease risk, suggesting a multi-omic approach is essential for personalized prevention.
Conomos, Matthew P +7 more
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Genetic predisposition to cancer [PDF]
British Journal of Cancer, 1991 BAJ Ponder
openalex +3 more sources
Genetic Predisposition to Clonal Hematopoiesis
HemaSphere, 2023 Pedro M. Quiros, George S. Vassiliou
doaj +4 more sources
Genetic predisposition in nonalcoholic fatty liver disease [PDF]
Clinical and Molecular Hepatology, 2017 Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when severe clinical forms, including nonalcoholic ...
Silvia Sookoian, Carlos J. Pirola
doaj +2 more sources
Physical frailty, genetic predisposition, and incident arrhythmias. [PDF]
J Cachexia Sarcopenia MuscleBackground Cross‐sectional evidence suggests a possible link between frailty and atrial fibrillation (AF). It remains unclear whether frailty and incident arrhythmias are longitudinally associated.
Zhang Y +6 more
europepmc +2 more sources
Grip strength, genetic predisposition, and Incident Parkinson's disease: a prospective cohort study in the UK Biobank. [PDF]
NPJ Parkinsons DisTo examine the association and modifiable risk factors between grip strength (GS) and Parkinson’s disease (PD) incidence considering genetic factors, a total of 411,648 individuals without PD at baseline from the UK Biobank were included. GS was measured
Hu W, Zhao CH, Huang YQ, Liu BP, Jia CX.
europepmc +2 more sources
Genetic Predisposition to Colorectal Cancer: How Many and Which Genes to Test?
International Journal of Molecular Sciences, 2023 Colorectal cancer is one of the most common tumors, and genetic predisposition is one of the key risk factors in the development of this malignancy. Lynch syndrome and familial adenomatous polyposis are the best-known genetic diseases associated with ...
F. Rebuzzi, P. Ulivi, G. Tedaldi
semanticscholar +1 more source
Network location and clustering of genetic mutations determine chronicity in a stylized model of genetic diseases [PDF]
Sci Rep 12, 19906 (2022), 2022 In a highly simplified view, a disease can be seen as the phenotype emerging from the interplay of genetic predisposition and fluctuating environmental stimuli. We formalize this situation in a minimal model, where a network (representing cellular regulation) serves as an interface between an input layer (representing environment) and an output layer ...
arxiv +1 more source
Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing. [PDF]
PLoS ONE, 2017 Genetic predisposition increases the risk of familial breast cancer. Recent studies indicate that genetic predisposition for familial breast cancer can be ethnic-specific.
Yeong C Kim +10 more
doaj +1 more source
Genetic predisposition to helminthiases [PDF]
Russian Journal of Genetics: Applied Research, 2013 Helminthes accompany human beings from the early period of the formation, there is a long-term coevolution between parasite and human, helminthes represent a major selective force for human immune genes. Data on genetic control of the intensity and clinical traits of helminthinfection in different populations, including results obtained by whole-genome
Irina V. Saltykova +3 more
openaire +2 more sources