Unique Features of Germline Variation in Five Egyptian Familial Breast Cancer Families Revealed by Exome Sequencing. [PDF]
PLoS ONE, 2017 Genetic predisposition increases the risk of familial breast cancer. Recent studies indicate that genetic predisposition for familial breast cancer can be ethnic-specific.
Yeong C Kim +10 more
doaj +1 more source
Genetic predisposition for Type 2 diabetes, but not for overweight/obesity, is associated with a restricted adipogenesis. [PDF]
PLoS ONE, 2011 BACKGROUND: Development of Type 2 diabetes, like obesity, is promoted by a genetic predisposition. Although several genetic variants have been identified they only account for a small proportion of risk.
Peter Arner +3 more
doaj +1 more source
Genetic predisposition to helminthiases [PDF]
Russian Journal of Genetics: Applied Research, 2013 Helminthes accompany human beings from the early period of the formation, there is a long-term coevolution between parasite and human, helminthes represent a major selective force for human immune genes. Data on genetic control of the intensity and clinical traits of helminthinfection in different populations, including results obtained by whole-genome
Irina V. Saltykova +3 more
openaire +2 more sources
Genetic predisposition to cancer [PDF]
Clinical Medicine, 2005 Over recent decades a number of genes causing predisposition to cancer have been identified. Some of these cause rare autosomal dominant monogenic cancer predisposition syndromes. In the majority of families, the increased incidence of cancers is due to a multifactorial aetiology with a number of lower penetrance cancer predisposition genes interacting
Shirley Hodgson, Clare Turnbull
openaire +3 more sources
Lessons From Pediatric MDS: Approaches to Germline Predisposition to Hematologic Malignancies
Frontiers in Oncology, 2022 Pediatric myelodysplastic syndromes (MDS) often raise concern for an underlying germline predisposition to hematologic malignancies, referred to as germline predisposition herein.
Serine Avagyan, Akiko Shimamura
doaj +1 more source
Genetic predisposition for cervical cancer
Акушерство, гинекология и репродукция, 2020 Aim: to assess a role of genetic factors and human papillomavirus (HPV) in developing cervical neoplasia based on analyzing current publications on virus-induced carcinogenesis.Materials and methods.
T. V. Rotaru +2 more
doaj +1 more source
Modifier genes and Lynch syndrome: some considerations
Hereditary Cancer in Clinical Practice, 2022 Lynch Syndrome (LS) is a highly variable entity with some patients presenting at very young ages with malignancy whereas others may never develop a malignancy yet carry an unequivocal genetic predisposition to disease.
Rodney J. Scott
doaj +1 more source
Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury [PDF]
, 2016 Context: Military recruits and elite athletes are susceptible to stress fracture injuries. Genetic predisposition has been postulated to have a role in their development.
A Gam +50 more
core +1 more source
Associations of clock genes polymorphisms with soft tissue sarcoma susceptibility and prognosis [PDF]
, 2018 BACKGROUND: Dysfunction of the circadian clock and polymorphisms of some circadian genes have been linked to cancer development and progression. We investigated the relationship between circadian genes germline variation and susceptibility or prognosis ...
Benna, Clara +6 more
core +2 more sources
Genetic Predisposition to Cutaneous Sarcoidosis [PDF]
Acta Medica Iranica, 2012 No ...
Nima Rezaei, Sepideh Shahkarami
doaj +2 more sources