Results 311 to 320 of about 353,849 (343)
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Genetic Predisposition, Humans
2014The translation from genetic knowledge to a molecular understanding of disease is contributing to the development of improved diagnostic and therapeutic products. Here, we examine the progress in molecular understanding of autoimmune disease that has been facilitated by genetic approaches, from candidate gene studies to genetic linkage and, more ...
Jordan, Margaret A. +3 more
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Genetic Predisposition Syndromes and Their Management
Surgical Clinics of North America, 2013Apart from BRCA1, BRCA2, and TP53, more than a dozen breast cancer susceptibility genes have been identified. Recognizing affected individuals depends on evaluation of cancer family history and recognition of certain phenotypic markers on physical examination. Genetic testing provides a powerful tool for individualized risk stratification.
David M. Euhus, Linda Robinson
openaire +3 more sources
Genetic Predisposition to IDDM
Clinical Reviews in Allergy & Immunology, 2000Sophie Caillat-Zucman +1 more
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Genetic predisposition to colorectal cancer
Nature Reviews Cancer, 2004High-penetrance mutations in several genes have been identified that contribute to hereditary colorectal cancer. The role of these mutations in cancer pathogenesis is well understood and their detection is successfully used in clinical diagnosis. In stark contrast, our understanding of the influence of low-penetrance mutations that account for most of ...
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Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Veda N Giri +2 more
exaly
Genetic Predisposition to Cardiomyopathies [PDF]
Pediatric Cardiology, 1997 openaire +2 more sources
Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Martin G Pomper, Steven P Rowe
exaly
Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly
Modern developments in germline pharmacogenomics for oncology prescribing
Ca-A Cancer Journal for Clinicians, 2022Natalie M Reizine, Peter H O'donnell
exaly