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Genetic Predisposition to Neonatal Tumors
Current Pediatric Reviews, 2015The development of tumors within the first month of life is extremely rare and this very young age at presentation should raise concern for an underlying cancer predisposition syndrome. This chapter discusses genetic predisposition to neonatal solid tumors, specifically those involving the eyes, kidneys, liver, adrenal glands and lungs.
Emily, Quinn +4 more
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Genetic Predisposition to IDDM
Clinical Reviews in Allergy & Immunology, 2000S, Caillat-Zucman, J F, Bach
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Genetic Predisposition for Gynecologic Cancers
Clinical Obstetrics & GynecologyHereditary cancer syndromes (HCS) are responsible for up to 10% of all cancers. At present, the majority of cancer susceptibility testing is initiated after a cancer diagnosis. There exists a significant opportunity for primary care providers including general obstetrician-gynecologists to engage in hereditary cancer risk assessment through adequate ...
Tavia, González Peña, Marilyn, Huang
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Genetic predisposition to colorectal cancer
Nature Reviews Cancer, 2004High-penetrance mutations in several genes have been identified that contribute to hereditary colorectal cancer. The role of these mutations in cancer pathogenesis is well understood and their detection is successfully used in clinical diagnosis. In stark contrast, our understanding of the influence of low-penetrance mutations that account for most of ...
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[Genetic predisposition for Alzheimer's disease].
Therapeutische Umschau. Revue therapeutique, 1996Alzheimer's disease comprises senile and presenile dementia. Aetiologically the disease is heterogeneous but has common clinical and pathological characteristics. Furthermore, in patients with a family history of dementia, its incidence is higher than in the general population.
M, Staufenbiel, E, Pombo-Villar
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