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Genetic Predisposition to Breast and Ovarian Cancers: How Many and Which Genes to Test?
Breast and ovarian cancers are some of the most common tumors in females, and the genetic predisposition is emerging as one of the key risk factors in the development of these two malignancies.
D. Angeli, S. Salvi, G. Tedaldi
semanticscholar +1 more source
Genetic predisposition for cervical cancer
Aim: to assess a role of genetic factors and human papillomavirus (HPV) in developing cervical neoplasia based on analyzing current publications on virus-induced carcinogenesis.Materials and methods.
T. V. Rotaru+2 more
doaj +1 more source
Modifier genes and Lynch syndrome: some considerations
Lynch Syndrome (LS) is a highly variable entity with some patients presenting at very young ages with malignancy whereas others may never develop a malignancy yet carry an unequivocal genetic predisposition to disease.
Rodney J. Scott
doaj +1 more source
Beyond Barker: Infant Mortality at Birth and Ischaemic Heart Disease in Older Age [PDF]
Adverse conditions in early life can have consequential impacts on individuals' health in older age. In one of the first papers on this topic, Barker and Osmond 1986 show a strong positive relationship between infant mortality rates in the 1920s and ischaemic heart disease in the 1970s.
arxiv +1 more source
Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate with preeclampsia in the maternal ...
V. Steinthorsdottir+96 more
semanticscholar +1 more source
To assess whether women with a genetic predisposition to medical conditions known to increase pre‐eclampsia risk have an increased risk of pre‐eclampsia in pregnancy.
K. Gray+18 more
semanticscholar +1 more source
Genetic Predisposition to Cutaneous Sarcoidosis [PDF]
No ...
Nima Rezaei, Sepideh Shahkarami
doaj +2 more sources
Background The predictive relationship between mild-to-moderate alcohol consumption and the risk of incident atrial fibrillation (AF) remains controversial.
Chan Soon Park+9 more
doaj +1 more source
Discovering Behavioral Predispositions in Data to Improve Human Activity Recognition [PDF]
The automatic, sensor-based assessment of challenging behavior of persons with dementia is an important task to support the selection of interventions. However, predicting behaviors like apathy and agitation is challenging due to the large inter- and intra-patient variability.
arxiv +1 more source
Common genetic predisposition for heart failure and cancer
Cardiovascular diseases and cancer are major causes of mortality in industrialized societies. They share common risk factors (e.g., genetics, lifestyle, age, infection, toxins, and pollution) and might also mutually promote the onset of the respective ...
T. Pfeffer+2 more
semanticscholar +1 more source