Results 31 to 40 of about 364,926 (322)

A continuum of psychosis, one human gene, and not much else - the case for homogeneity [PDF]

, 1995
The contention of this paper is that psychoses are not a collection of separate and unrelated diseases, but a set of diverse expressions of a single underlying entity.
Crow, Prof TJ
core   +1 more source

Smoking during pregnancy is associated with child overweight independent of maternal pre-pregnancy BMI and genetic predisposition to adiposity

Scientific Reports, 2022
High maternal body mass index (BMI) and smoking during pregnancy are risk factors for child overweight. Maternal smoking tends to reduce her BMI and the association of smoking with child overweight may be confounded by or interacting with maternal ...
Theresia M. Schnurr, Lars Ängquist, Ellen Aagaard Nøhr, Torben Hansen, Thorkild I. A. Sørensen, Camilla S. Morgen   +5 more
doaj   +1 more source

Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients. [PDF]

, 2017
PurposeMany women with an elevated risk of hereditary breast and ovarian cancer have previously tested negative for pathogenic mutations in BRCA1 and BRCA2. Among them, a subset has hereditary susceptibility to cancer and requires further testing.
Adams, Sophie B, Chan, Salina, Crawford, Beth, Gil, Elad, Leitner, Ofri, Ryan, Lauren, Sittler, Taylor, van 't Veer, Laura, van den Akker, Jeroen   +8 more
core   +1 more source

Investigating the association of rs2910164 with cancer predisposition in an Irish cohort. [PDF]

, 2017
IntroductionMicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA).
Bell, M, Guerin, C, Kerin, MJ, Lowery, AJ, McVeigh, TP, McVeigh, UM, Miller, N, Mulligan, RJ, Owens, PW, Quill, DS, Sebag, F, Weidhaas, JB   +11 more
core   +3 more sources

Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition [PDF]

, 2016
Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells.
Chaudhry, MS, Gilmour, KC, House, IG, Layton, M, Panoskaltsis, N, Sohal, M, Trapani, JA, Voskoboinik, I   +7 more
core   +1 more source

Genetic predisposition in pediatric oncology

Medicine and Pharmacy Reports, 2020
Identifying patients with a genetic predisposition for developing malignant tumors has a significant impact on both the patient and family. Recognition of genetic predisposition, before diagnosing a malignant pathology, may lead to early diagnosis of a neoplasia.
Emilia Mihut, Diana Olteanu, Rodica Cosnarovici, Viorica Nagy, Doina Paula Pruteanu   +4 more
openaire   +3 more sources

Genetic predisposition for ovarian cancer development [PDF]

Arhiv za farmaciju
Ovarian cancer is a leading malignancy in the female reproductive system and is responsible for more deaths than any other type of cancer affecting this system. Ovarian cancers can be hereditary or sporadic.
Joksić Ivana, Prosenc-Zmrzljak Uršula, Ninić Ana, Ratković Tamara, Munjas Jelena   +4 more
doaj   +1 more source

Genetic Predisposition to Recurrent Aphthous Stomatitis

Česká Stomatologie a Praktické Zubní Lékařství, 2017
Background: Recurrent aphthous stomatitis (RAS), one of the most common diseases of the oral mucosa, is characterized by the formation of painful oral erosions or even ulcers.
P. Bořilová Linhartová, S. Valová, L. Izakovičová Hollá   +2 more
doaj   +1 more source

Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing

Scientific Reports, 2023
Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to childhood cancer are still under intense investigation.
Piedad Alba-Pavón, Lide Alaña, Miriam Gutierrez-Jimeno, Susana García-Obregón, Teresa Imízcoz, Elena Panizo, Paula González-Urdiales, Aizpea Echebarria-Barona, Ricardo Lopez Almaraz, Laura Zaldumbide, Itziar Astigarraga, Ana Patiño-García, Olatz Villate   +12 more
doaj   +1 more source

Genetic Predisposition to Primary Lactose Intolerance Does Not Influence Dairy Intake and Health-Related Quality of Life in Romanian Children: A Hospital-Based Cross-Sectional Study

Children, 2023
Background: Primary lactose intolerance (PLI) is characterized by the inability to digest lactose. Homozygotes for the lactase gene polymorphisms (CC or GG) are considered to be genetically predisposed to PLI. Still, symptoms may only be present later in
Corina Pienar, Liviu Pop, Marilena Lăzărescu, Radmila Costăchescu, Mirela Mogoi, Ruxandra Mare, Edward Șeclăman   +6 more
doaj   +1 more source