Results 41 to 50 of about 353,849 (343)
A continuum of psychosis, one human gene, and not much else - the case for homogeneity [PDF]
, 1995 The contention of this paper is that psychoses are not a collection of separate and unrelated diseases, but a set of diverse expressions of a single underlying entity.
Crow, Prof TJ
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Investigating the association of rs2910164 with cancer predisposition in an Irish cohort. [PDF]
, 2017 IntroductionMicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA).
Bell, M +11 more
core +3 more sources
Genetic predisposition to cancer
Medicine, 2008 Over the last 28 years there has been a burgeoning development of genetic risk assessment and ‘family history’ clinics to deal with the ever-increasing demand from individuals at increased risk of cancer by virtue of their family history. Risk of inherited cancer can be divided into known syndromes, such as familial polyposis, and increased risk of ...
openaire +3 more sources
Genetic predispositions to childhood leukemia [PDF]
Therapeutic Advances in Hematology, 2013 While the majority of leukemia cases occur in the absence of any known predisposing factor, there are germline mutations that significantly increase the risk of developing hematopoietic malignancies in childhood. In this review article, we describe a number of these mutations and their clinical features. These predispositions can be broadly classified
Stieglitz, Elliot, Loh, Mignon L
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Genetic predisposition for ovarian cancer development [PDF]
Arhiv za farmacijuOvarian cancer is a leading malignancy in the female reproductive system and is responsible for more deaths than any other type of cancer affecting this system. Ovarian cancers can be hereditary or sporadic.
Joksić Ivana +4 more
doaj +1 more source
Prevalence and breed predisposition for thoracolumbar intervertebral disc disease in cats [PDF]
, 2016 Objectives The objective was to evaluate the prevalence and possible breed predilections for thoracolumbar intervertebral disc disease (IVDD) in cats. Methods Medical records and imaging studies of cats diagnosed with thoracolumbar IVDD between January ...
De Decker, S, Volk, H A, Warner, A-S
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Whither Pediatric Research and Predisposition Genetic Testing? [PDF]
, 2006 [À l'origine dans / Was originally part of : CRDP - Droit, biotechnologie et rapport au milieu]Research in which children undergo genetic testing for predisposition to adult-onset diseases or disorders can lead to a better understanding of these ...
Avard, Denise +2 more
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FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Frontiers in Genetics, 2022 Sequencing technologies can inform individuals’ risks for multiple conditions, supporting population-level screening approaches. Prior research examining interest in genetic testing has not generally examined the context of population-based approaches ...
Kimberly A. Kaphingst +7 more
doaj +1 more source
Exploring the role of fallopian ciliated cells in the pathogenesis of high-grade serous ovarian cancer [PDF]
, 2018 High-grade serous epithelial ovarian cancer (HGSOC) is the fifth leading cause of cancer death in women and the first among gynecological malignancies. Despite an initial response to standard chemotherapy, most HGSOC patients relapse.
Baldassarre G +9 more
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