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Understanding the Use of Genetic Predisposition in Canadian Legal Decisions [PDF]
, 2013 Since the advent of the Human Genome Project in 1989, the ethical. legal, and social implications inherent in future genetic science and its applications have worried researchers and scholars in law and ethics. Concern that the results of genetic testing
Finkler, Lilith +3 more
core +3 more sources
Children, 2023 Background: Primary lactose intolerance (PLI) is characterized by the inability to digest lactose. Homozygotes for the lactase gene polymorphisms (CC or GG) are considered to be genetically predisposed to PLI. Still, symptoms may only be present later in
Corina Pienar +6 more
doaj +1 more source
The potential for misusing genetic predisposition in Canadian courts and tribunals [PDF]
, 2011 The fulfilment of promises made 25 years ago to link clinical conditions with gene sequences has allowed patients and families to better understand hereditary conditions and make choices regarding prevention, early detection and treatment.
Finkler, Lilith +3 more
core +2 more sources
Genetic predisposition to MDS: clinical features and clonal evolution.
Blood, 2019 Myelodysplastic syndrome (MDS) typically presents in older adults with the acquisition of age-related somatic mutations, whereas MDS presenting in children and younger adults is more frequently associated with germline genetic predisposition.
A. Kennedy, A. Shimamura
semanticscholar +1 more source
Importance of Understanding Genetic Predisposition [PDF]
, 2021 Hypersensitivity reactions can be sudden and are often fatal. Many of these reactions occur as a result of allergies to prescribed medication. Adverse drug reactions or (ADR’s) were show in a recent study to affect over 6% of hospitalized patients and ...
Carter, Andrew
core +1 more source
Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility [PDF]
, 2021 Background: Serrated polyposis syndrome (SPS) is a clinical entity characterised by large and/ormultiple serrated polyps throughout the colon and increased risk for colorectal cancer (CRC).
Arnau Collell, Coral +20 more
core +1 more source
Current status of liver transplantation for non‐B non‐C liver cirrhosis and hepatocellular carcinoma
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 42-52, January 2023., 2023 Recently, the cases of LT for non‐B non‐C cirrhosis and HCC have been increasing in Japan as well as worldwide. Perioperative management of non‐B non‐C liver disease is problematic due to various risk factors, including alcohol consumption and metabolic syndrome‐related risks, such as obesity and diabetes mellitus.
Takahiro Nishio +4 more
wiley +1 more source
Scientific Reports, 2023 Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to childhood cancer are still under intense investigation.
Piedad Alba-Pavón +12 more
doaj +1 more source
Prenatal Sugar Consumption and Late-Life Human Capital and Health: Analyses Based on Postwar Rationing and Polygenic Scores [PDF]
arXiv, 2023 Maternal sugar consumption in utero may have a variety of effects on offspring. We exploit the abolishment of the rationing of sweet confectionery in the UK on April 24, 1949, and its subsequent reintroduction some months later, in an era of otherwise uninterrupted rationing of confectionery (1942-1953), sugar (1940-1953) and many other foods, and we ...
arxiv
On-off intermittency of thalamo-cortical oscillations in the electroencephalogram of rats with genetic predisposition to absence epilepsy [PDF]
Brain research. 1436 (2012) 147-156, 2013 Spike-wave discharges (SWD) are electroencephalographic hallmarks of absence epilepsy. SWD are known to originate from thalamo-cortical neuronal network that normally produce sleep spindle oscillations. Although both sleep spindles and SWD are considered as thalamo-cortical oscillations, functional relationship between them is still uncertain.
arxiv +1 more source