Results 61 to 70 of about 2,938,873 (406)
Genetic predisposition in pediatric oncology
Medicine and Pharmacy Reports, 2020 Identifying patients with a genetic predisposition for developing malignant tumors has a significant impact on both the patient and family. Recognition of genetic predisposition, before diagnosing a malignant pathology, may lead to early diagnosis of a neoplasia.
Emilia Mihut +4 more
openaire +3 more sources
Leveraging eQTLs to identify individual-level tissue of interest for a complex trait.
PLoS Computational Biology, 2021 Genetic predisposition for complex traits often acts through multiple tissues at different time points during development. As a simple example, the genetic predisposition for obesity could be manifested either through inherited variants that control ...
Arunabha Majumdar +8 more
doaj +1 more source
Comparing Psychometric and Behavioral Predictors of Compliance During Human-AI Interactions [PDF]
, 2023 Optimization of human-AI teams hinges on the AI's ability to tailor its interaction to individual human teammates. A common hypothesis in adaptive AI research is that minor differences in people's predisposition to trust can significantly impact their likelihood of complying with recommendations from the AI.
arxiv +1 more source
Genetic predisposition in nonalcoholic fatty liver disease [PDF]
Clinical and Molecular Hepatology, 2017 Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when severe clinical forms, including nonalcoholic ...
Silvia Sookoian, Carlos J. Pirola
doaj +1 more source
Androgenetic alopecia: a review [PDF]
, 2017 Purpose Androgenetic alopecia, commonly known as male pattern baldness, is the most common type of progressive hair loss disorder in men. The aim of this paper is to review recent advances in understanding the pathophysiology and molecular mechanism
Caro, Gemma +7 more
core +1 more source
Genetic predisposition to mosaic Y chromosome loss in blood
bioRxiv, 2019 Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common form of clonal mosaicism1–5, yet our knowledge of the causes and consequences of this is limited. Here, using a computational approach, we estimate that 20% of the male
Deborah J. Thompson +50 more
semanticscholar +1 more source
Genetic Predisposition to Recurrent Aphthous Stomatitis
Česká Stomatologie a Praktické Zubní Lékařství, 2017 Background: Recurrent aphthous stomatitis (RAS), one of the most common diseases of the oral mucosa, is characterized by the formation of painful oral erosions or even ulcers.
P. Bořilová Linhartová +2 more
doaj +1 more source
Genetic predisposition to cancer
Medicine, 2008 Over the last 28 years there has been a burgeoning development of genetic risk assessment and ‘family history’ clinics to deal with the ever-increasing demand from individuals at increased risk of cancer by virtue of their family history. Risk of inherited cancer can be divided into known syndromes, such as familial polyposis, and increased risk of ...
openaire +3 more sources
Genetic predispositions to childhood leukemia [PDF]
Therapeutic Advances in Hematology, 2013 While the majority of leukemia cases occur in the absence of any known predisposing factor, there are germline mutations that significantly increase the risk of developing hematopoietic malignancies in childhood. In this review article, we describe a number of these mutations and their clinical features. These predispositions can be broadly classified
Stieglitz, Elliot, Loh, Mignon L
openaire +3 more sources
Journal of Pathology, 2019 This article reviews genes and syndromes associated with predisposition to colorectal cancer (CRC), with an overview of gene variant classification. We include updates on the application of preventive and therapeutic measures, focusing on the use of non ...
L. Valle +3 more
semanticscholar +1 more source