Results 71 to 80 of about 350,999 (265)
CLINICAL AND GENETIC PARALLELS ALONG CELIAC DISEASE AMONG TOMSK CHILDREN
The article is devoted to the analysis of the genetic predisposition to celiac disease. The authors studied the associations of the HLA genes and modifier genes of the immune response (interleukine 1, inter leukine 1 receptor antagonist, inter leukine 4,
E.I. Kondrat’eva+5 more
doaj +2 more sources
Symposium 6: HLA and Non-HLA genetic predisposition
Symposium 6: Autoimmune diabetes: heterogeneity in its clinical presentations HLA and Non-HLA genetic predisposition Type 1 diabetes is a multifactorial autoimmune disease.
Gloria Cerrone
doaj +1 more source
Understanding the Use of Genetic Predisposition in Canadian Legal Decisions [PDF]
Since the advent of the Human Genome Project in 1989, the ethical, legal, and social implications inherent in future genetic science and its applications have worried researchers and scholars in law and ethics. Concern that the results of genetic testing
Finkler, Lilith+3 more
core +1 more source
Genetic Predisposition to Infectious Disease [PDF]
In contemporary medical practice, approaches to infectious disease management have been primarily rooted in a pathogen-centered model. However, host genetics also contribute significantly to infectious disease burden. The fast expansion of bioinformatics techniques and the popularization of the genome-wide association study (GWAS) in recent decades ...
openaire +3 more sources
Myelodysplastic syndrome with genetic predisposition
Myelodysplastic syndrome (MDS) refers to a heterogeneous group of clonal blood disorders characterized by ineffective hematopoiesis, cytopenia, dysplasia, and an increased risk of acute myeloid leukemia (AML). A growing number of inherited genetic loci that contribute to MDS/AML development are rapidly being identified. As genetic sequencing has become
openaire +4 more sources
Prevalence and breed predisposition for thoracolumbar intervertebral disc disease in cats [PDF]
Objectives The objective was to evaluate the prevalence and possible breed predilections for thoracolumbar intervertebral disc disease (IVDD) in cats. Methods Medical records and imaging studies of cats diagnosed with thoracolumbar IVDD between January ...
De Decker, S, Volk, H A, Warner, A-S
core +1 more source
Understanding the molecular basis of leukaemia predisposition is essential for intervention. The authors here investigate germline genetic leukaemia predisposition by studying Shwachman-Diamond syndrome and report compensatory inactivating mutations in ...
Alyssa L. Kennedy+42 more
doaj +1 more source
Genetic Basis of Familial Lymphoma Predisposition [PDF]
Lymphomas are classified into Hodgkin and non-Hodgkin lymphomas (HL and NHL), and they are further categorized into tens of different subtypes. This thesis has focused on two rare lymphoma subtypes: nodular lymphocyte predominant Hodgkin lymphoma (NLPHL)
Saarinen, Silva
core
The association of genetic predisposition to depressive symptoms with non-suicidal and suicidal self-Injuries [PDF]
Non-suicidal and suicidal self-injury are very destructive, yet surprisingly common behaviours. Depressed mood is a major risk factor for non-suicidal self-injury (NSSI), suicidal ideation and suicide attempts.
Abdellaoui, Abdel+13 more
core +3 more sources
How intelligence can change the course of evolution [PDF]
The effect of phenotypic plasticity on evolution, the so-called Baldwin effect, has been studied extensively for more than 100 years. Plasticity is known to influence the speed of evolution towards a specific genetic configuration, but whether it also influences what that genetic configuration is, is still an open question.
arxiv