Results 161 to 170 of about 185,084 (189)

Genetic Predisposition to Parkinson’s Disease and Cancer

Current Cancer Drug Targets, 2014
Parkinson's disease (PD) and cancer are often thought of as two sides of the same coin. At first glance, cancer and PD appear to have little in common. PD is caused by the degeneration of dopaminergic neurons, whereas cancer results from the uninhibited growth of tumor cells. Increasing numbers of genetic studies suggest that the pathogenesis of PD and
Zhiming, Li, Qing, Lin, Qilin, Ma, Congxia, Lu, Chi-Meng, Tzeng   +4 more
openaire   +2 more sources

Genetic predisposition to coronary artery disease

Current Opinion in Cardiology, 2001
Understanding the genetic basis of coronary artery disease (CAD) can improve management and prevention. Family and twin studies, animal models and gene association studies support a genetic basis for CAD. Genes contribute to CAD development and progression, and response to risk factor modification and lifestyle choices.
openaire   +2 more sources

Coronavirus: Pure Infectious Disease or Genetic Predisposition

2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes novel coronavirus disease (COVID-19), is the seventh pathogenic coronavirus recently discovered in December 2019 in Wuhan, China. To date, our knowledge about its effect on the human host remains limited.
Farzaneh Darbeheshti, Hassan Abolhassani, Mohammad Bashashati, Saeid Ghavami, Sepideh Shahkarami, Samaneh Zoghi, Sudhir Gupta, Jordan S. Orange, Hans D. Ochs, Nima Rezaei   +9 more
openaire   +2 more sources

Genetic predisposition to environmental induced diseases

Environmental Toxicology and Pharmacology, 1997
It is argued that genetic predispositions to environmentally induced illness are common in the general population. Yet, despite this, recognition assessment of the nature and magnitude of such predispositions has generally not been the object of environmental health research.
openaire   +2 more sources

[Genetic predisposition for Alzheimer's disease].

Therapeutische Umschau. Revue therapeutique, 1996
Alzheimer's disease comprises senile and presenile dementia. Aetiologically the disease is heterogeneous but has common clinical and pathological characteristics. Furthermore, in patients with a family history of dementia, its incidence is higher than in the general population.
M, Staufenbiel, E, Pombo-Villar
openaire   +2 more sources

GENETIC PREDISPOSITION TO DRUG-INDUCED LIVER DISEASE

Gastroenterology Clinics of North America, 1995
Rarely do otherwise safe drugs administered at recommended doses produce liver damage that may progress to liver failure and death. Because we are generally unable to identify the patients most susceptible to this "idiosyncratic" form of toxicity, many potentially useful medications are not made available to patients. The most promising developments in
R J, Fontana, P B, Watkins
openaire   +2 more sources

Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

The Lancet, 1991
The spongiform encephalopathy Creutzfeldt-Jakob disease (CJD) has been transmitted to man via administration of growth hormone and gonadotropin extracted from large pooled batches of human cadaveric pituitary glands. In the UK, 1908 individuals were exposed to potentially contaminated growth hormone, of whom 6 have so far manifested CJD. Examination of
J, Collinge, M S, Palmer, A J, Dryden
openaire   +2 more sources

[Genetic predisposition to cardiovascular diseases].

Przeglad lekarski, 2000
The development of cardiovascular system disorders depends on both environmental and genetic factors. Precise mechanism by which genetic factors may promote atherosclerotic lesion formation is still under investigation. From multiple candidate genes for cardiovascular disorders the special attention should be paid to that which control synthesis of ...
M, Stajszczyk, J, Gmiński
openaire   +1 more source

GENETIC FACTORS AND PREDISPOSITION TO DISEASE

This article reviews genetic factors that influence susceptibility to various diseases, including both hereditary and multifactorial disorders. The study relies on the analysis of existing data and the results of meta-analyses to substantiate the significance of genetic predisposition in disease pathogenesis.
Karimov Abduhalim Abdurozikovich, Hamidova Zebiniso Hikmatovna   +1 more
openaire   +1 more source

Genetic Predisposition to Hypertension and Cardiovascular Disease

2003
Essential hypertension occurs in individuals with a genetic predisposition who respond abnormally to environmental changes. A complex interplay of a number of genetic alterations and environmental factors is involved in the pathogenesis of hypertension.
Toshio Ogihara, Tomohiro Katsuya, Jitsuo Higaki   +2 more
openaire   +1 more source