Results 171 to 180 of about 187,732 (244)

Towards a WHO classification of genetic tumour syndromes. [PDF]

Med Genet
Siebert R, Foulkes WD.
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Defects in Innate and Intrinsic Immunity in Morocco: A Retrospective Analysis of the Genetic Landscape and Clinical Correlations. [PDF]

Pathog Immun
Refaat M, Oujane C, Errami A, Aadam Z, Moundir A, Baghad B, Zaidi S, Kholaiq H, El Kettani A, Benhsaien I, Ailal F, Bourhanbour AD, El Bakkouri J, Bousfiha AA.   +13 more
europepmc   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Preeclampsia, gestational hypertension, and cardiovascular disease risk: a genetic epidemiological study. [PDF]

Eur Heart J
Taageby Nielsen S, Luo J, Tybjærg-Hansen A, Iversen K, Bundgaard H, Qvist Thomassen J, Frikke-Schmidt R.   +6 more
europepmc   +1 more source

Genetic drivers of hippocampal atrophy highlight the role of APOE functional variants and AD polygenicity in Mild Cognitive Impairment. [PDF]

Neuroimage Clin
Vilor-Tejedor N, Rodrigo A, Genius P, Rodríguez-Fernández B, Anastasi F, Pelkmans W, Navarro A, Adams HH, Wisse L, Gispert JD, Evans TE, ADNI.   +11 more
europepmc   +1 more source

Cardiovascular Disease as a Predictor of Dementia: A Cross-National Ecological Study of 204 Countries. [PDF]

Health Sci Rep
You W.
europepmc   +1 more source

Exposure to Occupational Inhalants and the Risk of Developing Rheumatoid Arthritis: A Systematic Review and Meta‐Analysis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint pain, swelling, and stiffness. Although smoking is a well‐established risk factor for RA, the role of occupational inhalants in RA development is less well recognized.
Qianwen Liu, Xin Song, Emily Mauro, Yuan Jiang, Klementy Shchetynsky, Lars Klareskog, Lars Alfredsson, Xia Jiang   +7 more
wiley   +1 more source

Mitigation of Metabolic Diseases Through Personalized Nutrition: A Critical In-Depth Review. [PDF]

Food Sci Nutr
Arshad MT, Ali MKM, Awlqadr FH, Maqsood S, Ikram A, Hossain MS, Abdullahi MA, Rashed MM.   +7 more
europepmc   +1 more source