Results 211 to 220 of about 2,712,849 (369)

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus in Ghana – A single‐center study

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
This study describes the clinical and laboratory profile and outcomes of hospitalized COVID‐19 patients with type 2 diabetes mellitus (DM) in Ghana. Out of 175 patients (mean age 55.9+/−18.3 years) 64 (36.6%) had DM. Compared to non‐diabetics, DM patients were older (61.1? 12.8 vs. 53.0?
Yasmine Oladele Hardy, Elena Libhaber, Emmanuel Ofori, Divine Aseye Yao Amenuke, Samuel Amoabeng Kontoh, James Amoah Dankwah, Rita Larsen‐Reindorf, Caleb Otu‐Ansah, Kojo Hutton‐Mensah, Ebenezer Dadson, Sheila Adamu, Kofi Akyerekoh, Fred Stephen Sarfo, Bernard Nkum   +13 more
wiley   +1 more source

Genetic predisposition to inflammation: a new risk factor of Alzheimer’s disease

, 2008
Ying Wan, Gang Wang, Shengdi Chen
openalex   +2 more sources

Recurrent and Extensive Idiopathic Granulomatous Ureteritis: A Localized Hyperimmune Disease with Genetic Predisposition

, 2022
Kamel El-Reshaid, Amal A.A. Abd-El-Hafez, Siba El Hussein   +2 more
openalex   +2 more sources

Vitamin B12 Levels Association with Functional and Structural Biomarkers of Central Nervous System Injury in Older Adults

Annals of Neurology, EarlyView.
At low levels of B12, specifically when bound to transcobalamin for cellular uptake, evidence of slower conductivity in the brain could point toward impaired myelin. At high levels of B12, specifically when bound to the biologically inert transport protein haptocorrin, biomarkers of neurodegeneration appear in the serum, indicating neuroaxonal injury ...
Alexandra Beaudry‐Richard, Ahmed Abdelhak, Rowan Saloner, Simone Sacco, Shivany C. Montes, Frederike C. Oertel, Christian Cordano, Nour Jabassini, Kirtana Ananth, Apraham Gomez, Azeen Keihani, Makenna Chapman, Sree Javvadi, Shikha Saha, Adam Staffaroni, Christopher Songster, Martin Warren, John W. Boscardin, Joel Kramer, Bruce Miller, Joshua W. Miller, Ralph Green, Ari J. Green   +22 more
wiley   +1 more source

Genetic Predisposition of TNF-α (-308), TGF-β-1 (-508) and IL-35(EBI3) Gene Polymorphisms towards Rheumatic Heart Disease in the Population of Telangana from South India

, 2022
Prashant Chilliveri, Baluka Vanitha, Y. Shiva Kumar   +2 more
openalex   +1 more source

Genetic predisposition of Parkinson’s Disease

Japanese Journal of Pharmacology, 1998
N. Hattori, T. Kobayashi, S. Matsubayashi, Hiroto Matsumine, A. Yoritaka, Y. Mizuno   +5 more
openaire   +2 more sources

Psychoses of Epilepsy: Unravelling the Phenotypic and Genotypic Features

Annals of Neurology, EarlyView.
Objectives We analyzed the genotypic and phenotypic features of patients with psychosis of epilepsy (POE). Methods Patients with POE recruited to an epilepsy genetics research program underwent phenotyping and genetic analysis. The latter included screening for rare pathogenic variants in epilepsy genes, and polygenic risk score (PRS) calculation for ...
Genevieve Rayner, Eliza Honybun, Melanie Bahlo, Karen L. Oliver, Ingrid E. Scheffer   +4 more
wiley   +1 more source

Genetics-Driven Personalized Disease Progression Model [PDF]

arXiv
Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a uniform trajectory pattern at the population level. However, chronic diseases are highly heterogeneous and often have
arxiv  

The Role of Genetic Predisposition in Diagnosis and Therapy of Periodontal Diseases in Type 1 Diabetes Mellitus

, 2011
M Albrecht
openalex   +2 more sources