Results 271 to 280 of about 320,413 (381)

Serial Changes in Right Ventricular Outflow Tract Gradient and Endocarditis Risk After Transcatheter Pulmonary Valve Replacement

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Infective endocarditis (IE) after transcatheter pulmonary valve replacement (TPVR) remains a significant concern. Although there are overall good short‐term and long‐term hemodynamic outcomes, limited data exist comparing postimplantation echocardiographic findings leading to IE.
Juan C. Samayoa, Lauren Carlozzi, Connie Choi, William Tressel, Jack M. Wolf, Benjamin Langworthy, Agustin Rubio, Troy Johnston, Zachary L. Steinberg, Thomas Jones, Brian Morray   +10 more
wiley   +1 more source

Detecting likely germline variants during tumor-based molecular profiling. [PDF]

J Clin Invest
Jaber D, Zhang J, Godley LA.
europepmc   +1 more source

Navigating the Uncertainties of Antithrombotic Therapy After Transcatheter Patent Foramen Ovale Closure: A Comprehensive Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The patent foramen ovale (PFO), present in 25% of the population, can cause paradoxical embolism and stroke. Transcatheter PFO closure is the gold standard for recurrent embolism with significant inter‐atrial shunting, with recent trials confirming its superiority in reducing ischemic stroke recurrence over medical therapy.
Eirini Beneki, Kyriakos Dimitriadis, Nikolaos Pyrpyris, Georgios Tzimas, Ioannis Skalidis, David Meier, Panagiotis Antiochos, Panagiotis Kostakis, Efthymia Pavlou, Francesco Perone, Georgios Tsivgoulis, Constantina Aggeli, Ole de Backer, Konstantinos Tsioufis   +13 more
wiley   +1 more source

Cardiovascular Health Metrics, Genetic Susceptibility, and Incident Chronic Obstructive Pulmonary Disease: A Prospective Cohort Analysis. [PDF]

JACC Adv
Gao JW, You S, He WB, Huang ZG, Cai YW, Wu YB, Chen Q, Wang JF, Zhang HF, Zhang SL, Liu PM.   +10 more
europepmc   +1 more source

Genetic Discrimination and Health Care; Ethical Reflections [PDF]

, 1996
Rodriguez, Eduardo
core   +1 more source

NSAIDS AS MODULATORS OF CATION CHANNELS: FENAMATES REPURPOSING IN CHANNELOPATHIES

ChemMedChem, Accepted Article.
Cationic ion channels are transmembrane proteins that regulate the flux of cations (potassium, sodium, and calcium) across cell membrane, playing a pivotal role in many cellular functions. Disruptions of their activity can lead to the so‐called genetic or acquired channelopathies, a heterogeneous group of diseases that affect multiple human systems ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean-François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions

Cancer Nexus, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley   +1 more source

Genetic Predisposition of Metabolic Dysfunction-Associated Steatotic Liver Disease: A Population-based Genome-wide Association Study [PDF]

Shaowen Wang, C. H. Wang, Yu‐Ming Cheng, Chun‐Yi Chen, Tsung‐Han Hsieh, Chia‐Chi Wang, Jia‐Horng Kao   +6 more
openalex   +1 more source

RAB19, SERPINB9P1, and Pancreatitis in Patients Taking Azathioprine in Routine Clinical Practice: Genome and Transcriptome‐Wide Association Studies

Clinical Pharmacology &Therapeutics, EarlyView.
Azathioprine is used to treat several inflammatory and autoimmune diseases. However, its use is limited by serious adverse events, including acute pancreatitis. Prior studies have found an association between the HLA region and thiopurine‐induced acute pancreatitis (TIAP); however, in clinical practice, many patients with pancreatitis do not meet this ...
Shailja C. Shah, Tyler S. Reese, Laura L. Daniel, Jacy Zanussi, Alyson L. Dickson, Puran Nepal, Ran Tao, Tyne Miller‐Fleming, Peter Straub, Jennifer Maizel, Adriana M. Hung, Wei‐Qi Wei, Elizabeth J. Phillips, Nancy J. Cox, C. Michael Stein, QiPing Feng, Cecilia P. Chung   +16 more
wiley   +1 more source

Exploring the potential causal association between genetic factors for multiple sclerosis and genetic factors for kidney disease: A multivariate Mendelian randomization study. [PDF]

Medicine (Baltimore)
Peng S, Li K, Han L, Liu P.
europepmc   +1 more source