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Coronavirus: Pure Infectious Disease or Genetic Predisposition
2021Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes novel coronavirus disease (COVID-19), is the seventh pathogenic coronavirus recently discovered in December 2019 in Wuhan, China. To date, our knowledge about its effect on the human host remains limited.
Farzaneh Darbeheshti +9 more
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GENETIC PREDISPOSITION TO DRUG-INDUCED LIVER DISEASE
Gastroenterology Clinics of North America, 1995Rarely do otherwise safe drugs administered at recommended doses produce liver damage that may progress to liver failure and death. Because we are generally unable to identify the patients most susceptible to this "idiosyncratic" form of toxicity, many potentially useful medications are not made available to patients. The most promising developments in
Paul B. Watkins, Robert J. Fontana
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Genetic predisposition to environmental induced diseases
Environmental Toxicology and Pharmacology, 1997It is argued that genetic predispositions to environmentally induced illness are common in the general population. Yet, despite this, recognition assessment of the nature and magnitude of such predispositions has generally not been the object of environmental health research.
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Physical Frailty, Genetic Predisposition, and Incident Parkinson Disease
JAMA Neurology, 2023ImportanceCross-sectional evidence implicates high prevalent frailty in patients with Parkinson disease (PD), whereas the longitudinal association remains unknown.ObjectivesTo examine the longitudinal association of the frailty phenotype with the development of PD and to explore the modification role of genetic risk of PD in such an association.Design,
Zekun, Zheng +4 more
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Genetic predisposition to coronary artery disease
Current Opinion in Cardiology, 2001Understanding the genetic basis of coronary artery disease (CAD) can improve management and prevention. Family and twin studies, animal models and gene association studies support a genetic basis for CAD. Genes contribute to CAD development and progression, and response to risk factor modification and lifestyle choices.
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Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease
The Lancet, 1991The spongiform encephalopathy Creutzfeldt-Jakob disease (CJD) has been transmitted to man via administration of growth hormone and gonadotropin extracted from large pooled batches of human cadaveric pituitary glands. In the UK, 1908 individuals were exposed to potentially contaminated growth hormone, of whom 6 have so far manifested CJD. Examination of
Mark S. Palmer +2 more
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[Genetic predisposition for Alzheimer's disease].
Therapeutische Umschau. Revue therapeutique, 1996Alzheimer's disease comprises senile and presenile dementia. Aetiologically the disease is heterogeneous but has common clinical and pathological characteristics. Furthermore, in patients with a family history of dementia, its incidence is higher than in the general population.
M, Staufenbiel, E, Pombo-Villar
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Preimplantation diagnosis for diseases with genetic predisposition and nondisease testing
Expert Review of Molecular Diagnostics, 2002Preimplantation genetic diagnosis has become a method of choice in genetic practices. The present experience includes thousands of clinical cases of preimplantation genetic diagnosis, demonstrating the safety, accuracy and reliability of the technique and its clinical relevance for those at-risk couples who cannot accept traditional methods for ...
Yury Verlinsky, Anver Kuliev
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Genetic Predisposition to Hypertension and Cardiovascular Disease
2003Essential hypertension occurs in individuals with a genetic predisposition who respond abnormally to environmental changes. A complex interplay of a number of genetic alterations and environmental factors is involved in the pathogenesis of hypertension.
Toshio Ogihara +2 more
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Possible Neurophysiological Markers of Genetic Predisposition to Alzheimer’s Disease
Dementia and Geriatric Cognitive Disorders, 1998Visual-evoked potentials (VEP) to a flash were studied in the first-order relatives of patients with Alzheimer’s disease (AD) (mean age 38.2 ± 2.6 years) in comparison with the patients (mean age 61.9 ± 1.4 years) and age-matched normal controls. It was found that in the relatives of AD patients the latencies of N2, P3, N3 components were delayed ...
V.F. Fokin +3 more
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