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Genetic predisposition to coronary artery disease.
Current Opinion in Cardiology, 2001Understanding the genetic basis of coronary artery disease (CAD) can improve management and prevention. Family and twin studies, animal models and gene association studies support a genetic basis for CAD.
M. Scheuner
semanticscholar +4 more sources
Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease
The Lancet, 1991The spongiform encephalopathy Creutzfeldt-Jakob disease (CJD) has been transmitted to man via administration of growth hormone and gonadotropin extracted from large pooled batches of human cadaveric pituitary glands. In the UK, 1908 individuals were exposed to potentially contaminated growth hormone, of whom 6 have so far manifested CJD. Examination of
J. Collinge, M. Palmer, Aidan J. Dryden
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Possible Neurophysiological Markers of Genetic Predisposition to Alzheimer’s Disease
Dementia and Geriatric Cognitive Disorders, 1998Visual-evoked potentials (VEP) to a flash were studied in the first-order relatives of patients with Alzheimer’s disease (AD) (mean age 38.2 ± 2.6 years) in comparison with the patients (mean age 61.9 ± 1.4 years) and age-matched normal controls. It was found that in the relatives of AD patients the latencies of N2, P3, N3 components were delayed ...
N. Ponomareva +3 more
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Geographical similarity and differences in the burden and genetic predisposition of NAFLD
Hepatology, 2022NAFLD has become a major public health problem for more than 2 decades with a growing prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D).
T. Yip +8 more
semanticscholar +1 more source
Ethical aspects of genetic predisposition to disease
, 1991P. Grandjean
semanticscholar +2 more sources
New England Journal of Medicine, 1971
Systemic lupus erythematosus is a disease characterized by several immunologic abnormalities. We determined the HL-A antigens of 40 patients by a standard lymphocyte cytotoxicity test. Specificity HL-A8 was present in 33 per cent, and W15 (LND) in 40 per
F. Grumet +4 more
semanticscholar +1 more source
Systemic lupus erythematosus is a disease characterized by several immunologic abnormalities. We determined the HL-A antigens of 40 patients by a standard lymphocyte cytotoxicity test. Specificity HL-A8 was present in 33 per cent, and W15 (LND) in 40 per
F. Grumet +4 more
semanticscholar +1 more source
The Genetic Predisposition to Interstitial Lung Disease
Chest, 2002R. Bois
semanticscholar +3 more sources
Genetic Predisposition to Parkinson’s Disease and Cancer
Current Cancer Drug Targets, 2014Parkinson's disease (PD) and cancer are often thought of as two sides of the same coin. At first glance, cancer and PD appear to have little in common. PD is caused by the degeneration of dopaminergic neurons, whereas cancer results from the uninhibited growth of tumor cells. Increasing numbers of genetic studies suggest that the pathogenesis of PD and
Qing Lin +4 more
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Clinical Genetics, 2020
Diabetes mellitus, also known simply as diabetes, has been described as a chronic and complex endocrine metabolic disorder that is a leading cause of death across the globe. It is considered a key public health problem worldwide and one of four important
M. Sirdah, N. Reading
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Diabetes mellitus, also known simply as diabetes, has been described as a chronic and complex endocrine metabolic disorder that is a leading cause of death across the globe. It is considered a key public health problem worldwide and one of four important
M. Sirdah, N. Reading
semanticscholar +1 more source
Coronavirus: Pure Infectious Disease or Genetic Predisposition
2021Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes novel coronavirus disease (COVID-19), is the seventh pathogenic coronavirus recently discovered in December 2019 in Wuhan, China. To date, our knowledge about its effect on the human host remains limited.
Farzaneh Darbeheshti +9 more
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