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Human Genetic Predisposition to Diseases Caused by Viruses from Flaviviridae Family
Molecular Biology, 2018The identification of human predisposition genes to severe forms of infectious diseases is important for understanding the mechanisms of pathogenesis, as well as for the detection of the risk groups.
N. Yudin +4 more
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GENETIC PREDISPOSITION TO DRUG-INDUCED LIVER DISEASE
Gastroenterology Clinics of North America, 1995Rarely do otherwise safe drugs administered at recommended doses produce liver damage that may progress to liver failure and death. Because we are generally unable to identify the patients most susceptible to this "idiosyncratic" form of toxicity, many potentially useful medications are not made available to patients. The most promising developments in
Paul B. Watkins, Robert J. Fontana
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Genetic predisposition to environmental induced diseases
Environmental Toxicology and Pharmacology, 1997It is argued that genetic predispositions to environmentally induced illness are common in the general population. Yet, despite this, recognition assessment of the nature and magnitude of such predispositions has generally not been the object of environmental health research.
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[Genetic predisposition for Alzheimer's disease].
Therapeutische Umschau. Revue therapeutique, 1996Alzheimer's disease comprises senile and presenile dementia. Aetiologically the disease is heterogeneous but has common clinical and pathological characteristics. Furthermore, in patients with a family history of dementia, its incidence is higher than in the general population.
M, Staufenbiel, E, Pombo-Villar
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Genetic Predisposition to Hypertension and Cardiovascular Disease
2003Essential hypertension occurs in individuals with a genetic predisposition who respond abnormally to environmental changes. A complex interplay of a number of genetic alterations and environmental factors is involved in the pathogenesis of hypertension.
Toshio Ogihara +2 more
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The Journal of Periodontology, 1981
In the present study the function of the neutrophil, which exerts a major role in protection against bacterial infections, was assessed in patients with a family history of diabetes mellitus and severe periodontitis.
J. McMullen +3 more
semanticscholar +1 more source
In the present study the function of the neutrophil, which exerts a major role in protection against bacterial infections, was assessed in patients with a family history of diabetes mellitus and severe periodontitis.
J. McMullen +3 more
semanticscholar +1 more source
Preimplantation diagnosis for diseases with genetic predisposition and nondisease testing
Expert Review of Molecular Diagnostics, 2002Preimplantation genetic diagnosis has become a method of choice in genetic practices. The present experience includes thousands of clinical cases of preimplantation genetic diagnosis, demonstrating the safety, accuracy and reliability of the technique and its clinical relevance for those at-risk couples who cannot accept traditional methods for ...
Yury Verlinsky, Anver Kuliev
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Breast Cancer-Related Lymphedema and Genetic Predisposition: A Systematic Review of the Literature.
Lymphatic Research and Biology, 2019Background: Secondary lymphedema is a complication following breast cancer therapy and constitutes the main form of lymphedema in the western world.
J. Visser +4 more
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Arthritis & Rheumatism, 2005
OBJECTIVE To determine whether overexpression of BAFF can accelerate the development of systemic lupus erythematosus-associated end-organ disease in hosts with an underlying autoimmune diathesis.
W. Stohl +14 more
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OBJECTIVE To determine whether overexpression of BAFF can accelerate the development of systemic lupus erythematosus-associated end-organ disease in hosts with an underlying autoimmune diathesis.
W. Stohl +14 more
semanticscholar +1 more source
Genetic Susceptibility to Hidradenitis Suppurativa and Predisposition to Cardiometabolic Disease
JAMA DermatologyImportanceHidradenitis suppurativa (HS) is associated with an increased prevalence of cardiovascular diseases compared with the general population. Any association between polygenic risk for HS, risk of incident cardiometabolic outcomes, and the plasma proteome is unclear.ObjectiveTo investigate the genetic correlation between HS and cardiometabolic ...
Nielsen, Valdemar Wendelboe +14 more
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