Results 141 to 150 of about 377,378 (213)

Evolving multispectral sensor configurations using genetic programming for estuary health monitoring. [PDF]

J R Soc N Z
Rogers M, Azhar M, Schenone S, Thrush S, Xue B, Zhang M, Delmas P.   +6 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Using Multi-objective Grammar-based Genetic Programming to Integrate Multiple Social Theories in Agent-based Modeling. [PDF]

Evol Multicriterion Optim, 2021
Vu TM, Davies E, Buckley C, Brennan A, Purshouse RC.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Physics-informed genetic programming for discovery of partial differential equations from scarce and noisy data. [PDF]

J Comput Phys
Cohen BG, Beykal B, Bollas G.
europepmc   +1 more source

Estimation of COVID-19 Epidemiology Curve of the United States Using Genetic Programming Algorithm. [PDF]

Int J Environ Res Public Health, 2021
Anđelić N, Baressi Šegota S, Lorencin I, Jurilj Z, Šušteršič T, Blagojević A, Protić A, Ćabov T, Filipović N, Car Z.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Correction: Automated code development based on genetic programming in graphical programming language: A pilot study. [PDF]

PLoS One
Kodytek P, Bodzas A, Zidek J.
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Health prediction for king salmon via evolutionary machine learning with genetic programming. [PDF]

J R Soc N Z
Zhang F, Zhang Y, Casanovas P, Schattschneider J, Walker SP, Xue B, Zhang M, Symonds JE.   +7 more
europepmc   +1 more source