Results 141 to 150 of about 102,518 (248)

A genetic programming-based convolutional deep learning algorithm for identifying COVID-19 cases via X-ray images. [PDF]

Artif Intell Med, 2023
Najaran MHT.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Control of mammalian cell-based devices with genetic programming. [PDF]

Curr Opin Syst Biol, 2021
Dray KE, Edelstein HI, Dreyer KS, Leonard JN.   +3 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Sensing Through Tissues Using Diffuse Optical Imaging and Genetic Programming. [PDF]

Sensors (Basel)
Balasubramaniam GM, Hauptman A, Arnon S.
europepmc   +1 more source

Genetic Programming-Based Feature Selection for Emotion Classification Using EEG Signal. [PDF]

J Healthc Eng, 2022
Sakalle A, Tomar P, Bhardwaj H, Iqbal A, Sakalle M, Bhardwaj A, Ibrahim W.   +6 more
europepmc   +1 more source

Evolving Benchmark Functions to Compare Evolutionary Algorithms via Genetic Programming [PDF]

Yifan He, Claus Aranha
openalex   +1 more source

Assessing Genetic Diversity for a Pre-Breeding Program in Piaractus mesopotamicus by SNPs and SSRs [PDF]

, 2019
Vito A. Mastrochirico-Filho, Felipe del Pazo, Milene Elissa Hata, Gabriela Vanina Villanova, Fausto Foresti, Manuel Vera, Paulino Martı́nez, Fábio Porto‐Foresti, Diogo Teruo Hashimoto   +8 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Data-driven formulation of steel fiber pull-out force in cementitious composites using genetic programming. [PDF]

Sci Rep
Kooshkaki A, Emamian SA, Kazemi R, Gandomi AH.   +3 more
europepmc   +1 more source