Results 121 to 130 of about 3,303,031 (404)
Genetic characterization of Pepino mosaic virus isolates from Belgian greenhouse tomatoes reveals genetic recombination [PDF]
Over a period of a few years, Pepino mosaic virus (PepMV) has become one of the most important viral diseases in tomato production worldwide. Infection by PepMV can cause a broad range of symptoms on tomato plants, often leading to significant financial ...
Bragard, C.+7 more
core +3 more sources
The estimation of map distances from recombination values.
The genetic map is a tool to quantify the distance between genes on a chromosome, based on the observed frequency of crossovers during cell division.
D. D. Kosambi
semanticscholar +1 more source
Dinaciclib blocks CDK12 activity, leading to downregulation of BRCA1, and probably other proteins involved in homologous recombination, promoting nonhomologous end joining. In this scenario, the presence of ionising radiation triggers a p53‐dependent senescent response that yields increased radiosensitivity. Pan‐cyclin‐dependent‐kinase (CDK) inhibitors
Natalia García Flores+14 more
wiley +1 more source
Measuring Homologous Recombination Rates between Chromosomal Locations in Salmonella
Homologous recombination between two similar DNA molecules, plays an important role in the repair of double-stranded DNA breaks. Recombination can occur between two sister chromosomes, or between two locations of similar sequence identity within the same
Gerrit Brandis+2 more
doaj +1 more source
Analysis of Optimal Recombination in Genetic Algorithm for a Scheduling Problem with Setups [PDF]
In this paper, we perform an experimental study of optimal recombination operator for makespan minimization problem on single machine with sequence-dependent setup times ($1|s_{vu}|C_{\max}$). The computational experiment on benchmark problems from TSPLIB library indicates practical applicability of optimal recombination in crossover operator of ...
arxiv
The role of haplotype complementation and purifying selection in the genome evolution [PDF]
We discuss two different ways of chromosomes' and genomes' evolution. Purifying selection dominates in large panmictic populations, where Mendelian law of independent gene assortment is valid. If the populations are small, recombination processes are not
Cebrat, Stanislaw+2 more
core
Smc5/6 is required for repair at collapsed replication forks. [PDF]
In eukaryotes, three pairs of structural-maintenance-of-chromosome (SMC) proteins are found in conserved multisubunit protein complexes required for chromosomal organization.
Ampatzidou, Eleni+3 more
core +3 more sources
Genetic recombination in Pseudomonas aeruginosa.
Summary: Genetic recombination has been shown to occur in Pseudomonas aeruginosa. Crosses between 18 biochemical mutants of 4 strains were studied and, although non-random segregation was found for non-selective markers, it has not yet been possible to ...
B. Holloway
semanticscholar +1 more source
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang+3 more
wiley +1 more source
Scalability of Genetic Programming and Probabilistic Incremental Program Evolution [PDF]
This paper discusses scalability of standard genetic programming (GP) and the probabilistic incremental program evolution (PIPE). To investigate the need for both effective mixing and linkage learning, two test problems are considered: ORDER problem ...
Ondas, Radovan+2 more
core +2 more sources