Results 271 to 280 of about 8,942,317 (309)
Some of the next articles are maybe not open access.
Genetics of Variability of CHD Risk
International Journal of Epidemiology, 1989Many genetic and environmental factors act in combination to determine inter-individual variability in risk factor traits for coronary artery disease (CAD). Geneticists have focused on the study of continuously distributed biological traits such as total plasma cholesterol.
C F, Sing, P P, Moll
openaire +2 more sources
Genetic risk factors for melanoma
Human Genetics, 2009The genetic basis of melanoma is complex and has both inherited and acquired components. Different genomic approaches have been used to identify a number of inherited risk factors, which can be stratified by penetrance and prevalence. Rare high-penetrance factors are expressed in familial clustering of melanoma and include mutations in CDKN2A (encoding
Kathrine Damm, Meyle, Per, Guldberg
openaire +2 more sources
Annual Review of Medicine, 2014
Recent advances in genetic analysis especially DNA sequencing technology open a new strategy for adult disease prevention by genetic screening. Physicians presently treat disease pathology with less emphasis on disease risk prevention/reduction. Genetic screening has reduced the incidence of untreatable childhood genetic diseases and improved the care
C Thomas, Caskey +3 more
openaire +2 more sources
Recent advances in genetic analysis especially DNA sequencing technology open a new strategy for adult disease prevention by genetic screening. Physicians presently treat disease pathology with less emphasis on disease risk prevention/reduction. Genetic screening has reduced the incidence of untreatable childhood genetic diseases and improved the care
C Thomas, Caskey +3 more
openaire +2 more sources
Genetic risks in Perthes' disease
Clinical Genetics, 1976A population study of Perthes' disease in South Wales over a 25‐year period has shown a low risk of the disorder in relatives. The risk of Perthes' disease in sibs is under 1 % (2 in 323), while the risk to children of an affected parent is about 3 % (1 in 35) when adjusted for age of onset.
P S, Harper, B J, Brotherton, D, Cochlin
openaire +2 more sources
Genetic ascertainment with heterogeneous risk
American Journal of Medical Genetics, 1987AbstractAnalysis of the bias of ascertainment is reformulated to deal with more general patterns commonly encountered in practice. The goal is to provide a unifying theory that will both replace the traditional, rather piecemeal, treatment of the problem and free it from certain restrictive assumptions.
Edmond A. Murphy +4 more
openaire +2 more sources
Risks of Reproducing with a Genetic Disorder
Seminars in Reproductive Medicine, 2013Male-factor infertility is the cause of reproductive issues in many couples. For approximately 15% of these men, the origin of the infertility is genetic. These causes include both chromosomal and single-gene disorders frequently impacting spermatogenesis.
Melissa Ciano, Byler +1 more
openaire +2 more sources
Genetic Cancer Risk Assessment
Seminars in Oncology Nursing, 2011To describe critical elements of cancer risk assessment as identified through professional standards.Professional guidelines, policy statements, and other published literature.The continually increasing integration of genetics/genomics into oncology care mandates that oncology nurses be familiar with the cancer risk assessment process, complexities ...
openaire +2 more sources
Genetic Biomarkers of Cancer Risk
Seminars in Oncology Nursing, 2012To provide a review of genetic biomarkers of cancer risk and associated clinical implications.Published literature, evidence-based guidelines.Identification of the genetic variation associated with cancer risk enables the health care provider to stratify an individual's risk and personalize their cancer risk management.
openaire +2 more sources
Genetic polymorphism and cancer risk
Current Oncology Reports, 2000Inter-individual variability in carcinogen metabolism has been attributed in part to the polymorphic expression of several phase I and II detoxification enzymes. The role of these genetic polymorphisms in cancer susceptibility has been most extensively evaluated for isozymes of cytochrome P450 (CYP1A1, CYP2D6, and CYP2E1), N-acetyltransferase (NAT1 and
openaire +2 more sources
Empirical risks in genetic counseling
Social Biology, 1970(1970). Empirical risks in genetic counseling. Social Biology: Vol. 17, No. 3, pp. 207-212.
openaire +2 more sources