New developments in biotechnology applied to animals: An assessment of the adequacy and sufficiency of current EFSA guidance for animal risk assessment. [PDF]
EFSA Panel on Genetically Modified Organisms (GMO)+27 more
europepmc +1 more source
Objective We estimated the real‐world cost‐effectiveness of a standardized education and exercise therapy program (GLA:D) compared to usual care (UC) for people managing hip and/or knee osteoarthritis (HKOA). Methods We used a prospective matched cohort design to recruit people (aged >45 years) diagnosed with HKOA who used GLA:D or UC (not on a ...
Darren R. Mazzei+4 more
wiley +1 more source
Long-Read Sequencing and Structural Variant Detection: Unlocking the Hidden Genome in Rare Genetic Disorders. [PDF]
Moustakli E+11 more
europepmc +1 more source
Objective Social determinants of health (SDoH) can impact outcomes but are not routinely screened for in US outpatient rheumatology clinics. This study determined the feasibility of routine point‐of‐care SDoH screening among patients with systemic lupus erythematosus (SLE) and associated barriers and facilitators at the physician, care team, and ...
S. Sam Lim+11 more
wiley +1 more source
Improvement of medical images with multi-objective genetic algorithm and adaptive morphological transformations. [PDF]
Moradzadeh S, Mehrdad V.
europepmc +1 more source
Objective Cognitive impairment (CI) is common in patients with systemic lupus erythematosus (SLE). Despite its prevalence, the immune mechanisms are not well understood. We previously reported elevated serum levels of S100A8/A9 and matrix metalloproteinase 9 (MMP‐9) in patients with SLE and CI.
Carolina Muñoz‐Grajales+18 more
wiley +1 more source
Objective We assessed whether shared decision‐making (SDM), and patient acceptability, feasibility, and overall satisfaction with a computerized patient decision aid (PtDA) for patients with systemic lupus erythematosus (SLE), differs by PtDA setting, modality, and the viewing experience.
Jasvinder A. Singh+3 more
wiley +1 more source
Whole-genome phenotype prediction with machine learning: open problems in bacterial genomics. [PDF]
James T+3 more
europepmc +1 more source
Comparative analysis of cattle (Bos taurus, 2n = 60) and river buffalo (Bubalus bubalis, 2n = 50) genome assemblies reveals two evolutionary conserved inversions and invalid centromere-telomere orientation of some autosomes. [PDF]
Pistucci R+7 more
europepmc +1 more source
Explainable AI in early autism detection: a literature review of interpretable machine learning approaches. [PDF]
Agrawal R, Agrawal R.
europepmc +1 more source