Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: Results obtained with a mix of two recombinant Bet v 1 fragments and recombinant Bet v 1 trimer in a Swedish population before the birch pollen season☆☆☆★ [PDF]
Marianne van Hage+8 more
openalex +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Summary: There is increasing evidence of the clinical utility of genetic and genomic testing (GT); however, factors influencing personal utility of GT, especially in diverse, multilingual populations, remain unclear.
Priya N. Marathe+26 more
doaj
The clinical application and challenges of preimplantation genetic testing. [PDF]
Zhou F, Chen X, Liu S, Wang X.
europepmc +1 more source
Attitudes toward genetic testing for colon cancer risk. [PDF]
Ken R. Smith, Robert T. Croyle
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Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Barriers to clinical genetic testing in movement disorders. [PDF]
Yeow D, Rudaks LI, Kumar KR.
europepmc +1 more source
Gene-environment interaction in hereditary nonpolyposis colorectal cancer with implications for diagnosis and genetic testing [PDF]
Jae-Gahb Park+3 more
openalex +1 more source
5. Genetic Tests in Clinical Testing
Tadao Funato, Mayu Takeda
openaire +4 more sources
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source