Results 281 to 290 of about 1,951,570 (332)

TESTING THE ROLE OF BAJA CALIFORNIA GENERATING BIODIVERSITY: A TEST CASE CHARACTERIZING THE POPULATION GENETIC STRUCTURE OF CASSIN'S AUKLET (PTYCHORAMPHUS ALEUTICUS)

, 2012
Sarah J. Wallace
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Genetic Testing of Neurodevelopmental Disorders in Israel.

JAMA Netw Open
May D, Barshir R, Shahar M, Rose AJ, Shmueli D.   +4 more
europepmc   +1 more source

Preimplantation genetic testing for aneuploidy in young women with recurrent spontaneous abortion. [PDF]

Medicine (Baltimore)
Pan Z, Huang Q, Tang N, Tang H, Liang Z, Huang P.   +5 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Cost-effective and flexible preimplantation genetic testing (PGT) by nanopore adaptive sampling. [PDF]

J Nanobiotechnology
Zhang Z, He S, Ding T, Liang X, Fang C, Zeng H, Xu L, Li X, Jia L, Zhang S, Su W, Sun P, Yang J, Ren J, Lu S, Ren Z.   +15 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Employee Perspectives on Genetic Testing in the Workplace: Results from a National Survey. [PDF]

Public Health Genomics
Roberts JS, Uhlmann WR, Blasco D, Prince AER, McCain S, Pal S, Sanghavi K, Charnysh E, Lee C.   +8 more
europepmc   +1 more source

Congenital Viral Infection Risk: The Role of Parvovirus B19 and Cytomegalovirus Molecular Genetic Testing. [PDF]

Int J Mol Sci
Krumova S, Trifonova I, Hristova-Savova M, Veleva L, Stefanova R, Genova-Kalou P, Chaveeva P, Kalev V, Tilkova T, Vassilev T, Dimova I.   +10 more
europepmc   +1 more source

A missed opportunity for preventing CMMRD: is it time to include Lynch syndrome genes in prenatal genetic testing? [PDF]

BMJ Case Rep
Nair G, Cadenas N, Singh A.
europepmc   +1 more source