Results 231 to 240 of about 5,467,287 (313)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Novel Therapeutic Targets and Approaches, Genetic Markers and Signaling Pathways in Neoplasms-An Overview. [PDF]

Cells
Chudakova D.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

HLA allele DRB1*01:03: the genetic link to neutralizing IL-10 antibodies in inflammatory bowel disease. [PDF]

Signal Transduct Target Ther
Mattner J.
europepmc   +1 more source

Genetic predisposition of Asparaginase-induced hypertriglyceridemia in children with acute lymphoblastic leukemia: Two case reports and review of literature. [PDF]

World J Clin Pediatr
Krivosheina M, Bakaleiko V, Toshina Y, Baratashvili G, Sokolnikova P, Kalinina OV, Alieva A, Dinikina Y, Kostareva AA.   +8 more
europepmc   +1 more source

A Novel <i>LAMA5</i> Variant in Adult-Onset Focal Segmental Glomerulosclerosis: A Case Report. [PDF]

Case Rep Genet
Dahlan RA, Fairoozy RH.
europepmc   +1 more source

GENETIC AND CELLULAR THERAPIES

, 2005
openaire   +1 more source