Results 171 to 180 of about 1,509,260 (344)

Development of genetic tools for heterologous protein expression in a pentose-utilizing environmental isolate of Pseudomonas putida. [PDF]

Microb Biotechnol, 2023
Gauttam R, Eng T, Zhao Z, Ul Ain Rana Q, Simmons BA, Yoshikuni Y, Mukhopadhyay A, Singer SW.   +7 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments. [PDF]

J Cell Biol
Pasolli M, Meiring JCM, Conboy JP, Koenderink GH, Akhmanova A.   +4 more
europepmc   +2 more sources

Development and application of CRISPR-based genetic tools in Bacillus species and Bacillus phages. [PDF]

J Appl Microbiol, 2022
Song Y, He S, Jopkiewicz A, Setroikromo R, van Merkerk R, Quax WJ.   +5 more
europepmc   +1 more source

gap: Genetic Analysis Package [PDF]

A preliminary attempt at collecting tools and utilities for genetic data as an R package called gap is described. Genomewide association is then described as a specific example, linking the work of Risch and Merikangas (1996), Long and Langley (1997) for
Jing Hua Zhao
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Next-generation-based targeted sequencing as an efficient tool for the study of the genetic background in Hirschsprung patients [PDF]

, 2015
Berta Luzón‐Toro, Laura Espino‐Paisán, Raquel Fernandez, Marta Martín-Sánchez, Guillermo Antiñolo, Salud Borrego   +5 more
openalex   +1 more source

Automata-based Adaptive Behavior for Economical Modelling Using Game Theory

, 2006
In this chapter, we deal with some specific domains of applications to game theory. This is one of the major class of models in the new approaches of modelling in the economic domain.
Bertelle, Cyrille, Duchamp, Gérard Henry Edmond, Ghnemat, Rawan, Oqeili, Saleh   +3 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Editorial: Biochemical and genetic tools to investigate the underlying mechanisms and treatment of sensorimotor pathologies. [PDF]

Front Mol Neurosci, 2022
Hutson TH, Hervera A.
europepmc   +1 more source