Results 241 to 250 of about 1,035,101 (349)

An Improved Method for Agrobacterium-Mediated Genetic Transformation of Three Types of Lettuce. [PDF]

Plants (Basel)
Roche MC, Liu W, Hernández R.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Genetic transformation of the oilseed crop camelina using immature zygotic embryos. [PDF]

Plant Methods
Rezaeva BR, Otto I, Hensel G, Pouramini P, Peterson A, Kumlehn J.   +5 more
europepmc   +1 more source

<i>Agrobacterium</i>-mediated Genetic Transformation of Potato (<i>Solanum tuberosum</i> L.) var. Cardinal and Heera

, 2012
Asma Khatun, M.M. Hasan, MAA Bachchu, M. Moniruzzaman, K. M. Nasiruddin   +4 more
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Establishment and application of high-pressure propagation breeding (HPPB)-mediated genetic transformation system in citrus rootstocks. [PDF]

Plant Biotechnol J
Zhang SY, Luo RF, Wu YX, Zhang TT, Yusuf A, Wang N, Li M, Duan S, Duan S.   +8 more
europepmc   +1 more source

The effect of data transformation on the genetic parameter estimates of resistance to Cercospora Sojina Hara in soybean

, 2002
Geraldo de Amaral Gravina, Paulo Roberto Cecon, Sebastião Martins Filho, Carlos Sigueyuki Sediyama   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Pigments to precision: RUBY aiding genetic transformation and genome editing in wheat and barley. [PDF]

Physiol Mol Biol Plants
Prusty MR, Shatil-Cohen A, Kumar R, Sharma D, Minz-Dub A, Ezrati S, Hihinashvili A, Sharon A.   +7 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source