Results 271 to 280 of about 1,104,984 (330)

Prevalence and Clinical Associations of Germline DDR Variants in Prostate Cancer: Real-World Evidence from a 122-Patient Turkish Cohort. [PDF]

Genes (Basel)
Akay S, Ozdemir TR, Ozer Kaya O, Degirmenci M, Unal OU.   +4 more
europepmc   +1 more source

Trends in the global commercialization of genetically modified crops in 2023

Xingru Cheng, Haohui Li, Qiaoling Tang, Haiwen Zhang, Tao Liu, Youhua Wang   +5 more
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Proteomic analysis of altered urinary extracellular vesicle levels in breast cancer patients pre- and post-surgery. [PDF]

Transl Cancer Res
Jeanmard N, Bissanum R, Charoenlappanit S, Roytrakul S, Navakanitworakul R.   +4 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Reproductive performance, inbreeding evolution, and genetic diversity of the Venezuelan Carora cattle evaluated through pedigree analysis. [PDF]

Front Vet Sci
Cartuche-Macas LF, Perez-Gonzalez JR, Jimenez-Quintero EJ, Gutiérrez-Reinoso MA, Garcia-Flores J, García-Herreros M.   +5 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Planetary health diet index, genetic susceptibility and incident chronic kidney disease: a cohort study from the UK Biobank. [PDF]

J Nutr Health Aging
Lv D, Wang T, Fan J, Hong D, Chen Z, Xu Q, Zhou D, Xie X.   +7 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Understanding the Preferences of Genetic Tools and Extension Services for the Northern Australia Beef Industry. [PDF]

Animals (Basel)
Menchon P, Cosby A, Swain DL, Manning JK.   +3 more
europepmc   +1 more source