Results 271 to 280 of about 1,230,887 (337)

The Evolution of Genetic Variability at the LRRK2 Locus. [PDF]

Genes (Basel)
Guenther DT, Follett J, Amouri R, Sassi SB, Hentati F, Farrer MJ.   +5 more
europepmc   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Assessment of Germplasm Improvement in Three Farmed Grass Carp Populations Based on Genetic Variability. [PDF]

Biology (Basel)
Shen Z, Shao L, Liu X, Li H, Guo H, Qin L, Luo K, Li W, Wang J, Li S, Gu Q, Guo L, Huang X, Qin Q, Liu S.   +14 more
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Multi-environmental evaluation of barley core collection against spot blotch for genetic variability and identification of promising genotypes exhibiting resistance. [PDF]

BMC Plant Biol
Patel SS, Vaish SS, Jacob SR, Singh GP, Kaur V.   +4 more
europepmc   +1 more source

Genetical variability of excised-leaf water retention capability in wheat.

, 1988
Gnanasiri S. Premachandra, Tohru Shimada
openalex   +2 more sources

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Investigating the Presence and Genetic Variability of Porcine Circovirus Types 2 and 3 in Live Markets in Border Cities of Northeast China. [PDF]

Transbound Emerg Dis
Sun F, Li M, Li S, Yang Z.
europepmc   +1 more source