Results 231 to 240 of about 4,753,986 (376)

Long-term macular atrophy growth in neovascular age-related macular degeneration: influential factors and role of genetic variants [PDF]

Brice Nguedia Vofo, Yahel Shwartz, Yaacov Cnaany, Shlomit Jaskoll, Andrea M. Kramer, Sarah Elbaz-Hayoun, Batya Rinsky, Michelle Grunin, Liran Tiosano, Itay Chowers   +9 more
openalex   +1 more source

Supplementary Data from Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

, 2023
Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Giovanni Stracquadanio, Katherine Brown, P. Richter, Marsha D. Wallace, Elisabeth E. Bond, Natasha Sahgal, Samantha Moore, Svanhild Nornes, Sarah De Val, Mirvat Surakhy, David Sims, Xuting Wang, Douglas A. Bell, Jorge Zerón-Medina, Yanyan Jiang, Anderson J. Ryan, Joanna Selfe, Janet Shipley, Siddhartha Kar, Paul D.P. Pharoah, Chey Loveday, Rick Jansen, Lukasz F. Grochola, Claire Palles, Andrew Protheroe, Val Millar, Daniel Ebner, Meghana S. Pagadala, Sarah P. Blagden, Tim Maughan, Enric Domingo, Ian Tomlinson, Clare Turnbull, Hannah Carter, Gareth L. Bond   +37 more
openalex   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Genomic landscape of the Great Steppe: Genetic variants in healthy Kazakh individuals. [PDF]

Sci Data
Serikzhan A, Daniyarov A, Molkenov A, Akhmetova A, Abilova Z, Sharip A, Yerezhepov D, Rakhimova S, Kozhamkulov U, Kushugulova A, Askarova S, Sarbassov D, Akilzhanova A, Kairov U.   +13 more
europepmc   +1 more source

Molecular genetic testing and cohort analysis of 32 twin pairs with neurodevelopmental disorders-Reporting a novel de novo variant of TET3 [PDF]

Lianni Mei, Chunchun Hu, Guangbo Jin, Chuanhui Ge, Yiting Zhu, Dongyun Li, Wenzhu Peng, Huiping Li, Xiu Xu, Yan Jiang, Guoliang Xu, Qiong Xu   +11 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Pharmacogenomics Applied to Acute Leukemias: Identifying Clinically Relevant Genetic Variants. [PDF]

Biomedicines
Pessoa FMCP, Farias IM, Nogueira BMD, Machado CB, Barreto IV, Machado AKDC, de Morais GP, da Cunha LS, de Sousa Oliveira D, Thé AP, Ribeiro RM, Thé PMP, Moraes Filho MO, Moraes MEA, Moreira-Nunes CA.   +14 more
europepmc   +1 more source

Additional file 6 of Systematically identifying genetic signatures including novel SNP-clusters, nonsense variants, frame-shift INDELs, and long STR expansions that potentially link to unknown phenotypes existing in dog breeds

, 2023
Zicheng Li, Zuoheng Wang, Zhiyuan Chen, Heidi Voegeli, Judith H. Lichtman, Peter Smith, Ju Liu, Andrew T. DeWan, Josephine Hoh   +8 more
openalex   +1 more source

InterVar: Clinical Interpretation of Genetic Variants by the 2015 ACMG-AMP Guidelines.

American Journal of Human Genetics, 2017
Quan Li, Kai Wang
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source