Results 231 to 240 of about 1,262,664 (328)

Prevalence and Nationality Distribution of Known and Novel Genetic Variants in Children With Primary Ciliary Dyskinesia in the State of Qatar [PDF]

Atqah AbdulWahab, Reem Mohamed, Adila A. Hamid, Hadeel Alzoubi, Donald R. Love, Kelly Robinson, Ibrahim Janahi, Mutasim Abu‐Hasan   +7 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

CTLA4 genetic variants influence immune regulation and susceptibility of HPV associated cervical cancer. [PDF]

Discov Oncol
de Oliveira MC, Fortunato GM, da Silva PR, Pacheco BLB, da Silva MR, Brajão de Oliveira K.   +5 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Pharmacogenomics Applied to Acute Leukemias: Identifying Clinically Relevant Genetic Variants. [PDF]

Biomedicines
Pessoa FMCP, Farias IM, Nogueira BMD, Machado CB, Barreto IV, Machado AKDC, de Morais GP, da Cunha LS, de Sousa Oliveira D, Thé AP, Ribeiro RM, Thé PMP, Moraes Filho MO, Moraes MEA, Moreira-Nunes CA.   +14 more
europepmc   +1 more source

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

, 2008
Robert Graham, Chris Cotsapas, Leela Davies, Rachel Hackett, Christopher J. Lessard, Joanlise M Leon, Noël P. Burtt, Candace Guiducci, Melissa Parkin, Casey Gates, Robert M. Plenge, Timothy W. Behrens, Joan Wither, John D. Rioux, Paul R. Fortin, Deborah Cunninghame Graham, Andrew Wong, Timothy J. Vyse, Mark J. Daly, David Altshuler, Kathy L. Moser, Patrick M. Gaffney   +21 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Genetic variants underlying precancerous conditions of hepatocellular carcinoma. [PDF]

Int J Cancer
Guerrero JJG, Encarnacion PC, Del Rosario MAS, Ora MAS, Zhou J, Notarte KI, Li WC, Chang CW.   +7 more
europepmc   +1 more source