InterVar: Clinical Interpretation of Genetic Variants by the 2015 ACMG-AMP Guidelines.
American Journal of Human Genetics, 2017 Quan Li, Kai Wang
semanticscholar +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
From genetic variants to therapeutic targets: insights into understanding rheumatoid arthritis. [PDF]
Front ImmunolChen L, Zhao J, Meng Q.
europepmc +1 more source
Genetic variants of liver and pancreas mannosephosphate isomerase in the Guinea fowl.
, 1983 Kohji Shiraishi, Yasokazu Hirai
openalex +2 more sources
Genomic Classification and Genetic Relationships of a New Variant of Hepatitis A Virus Isolated in Cuba [PDF]
, 1999 Belkis Díaz +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Genetic Variants Related to Increased CKD Progression-A Systematic Review. [PDF]
Biology (Basel)Mira FS +4 more
europepmc +1 more source
Luteinizing Hormone and Different Genetic Variants, as Indicators of Frailty in Healthy Elderly Men [PDF]
, 1999 Annewieke W. van den Beld
openalex +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source