Results 251 to 260 of about 4,570,575 (370)

Genetic variants of myeloperoxidase and lung cancer risk [PDF]

, 2000
Matthew B. Schabath, Margaret R. Spitz, Xinmei Zhang, George L. Delclos, Xifeng Wu   +4 more
openalex   +3 more sources

Impact of Genetic Variants on Pregabalin Pharmacokinetics and Safety. [PDF]

Pharmaceuticals (Basel)
Calleja S, Rodríguez-López A, Ochoa D, Luquero S, Navares-Gómez M, Román M, Mejia-Abril G, Martín-Vilchez S, Abad-Santos F, Zubiaur P.   +9 more
europepmc   +1 more source

Proteins of the milk and genetic variants in certain sheep populations of Sicily (Barbaresca-Siciliana)

, 1982
L Chiofalo, P Micari
openalex   +2 more sources

HIV-1 Subtype F in Single and Dual Infections in Puerto Rico: A Potential Sentinel Site for Monitoring Novel Genetic HIV Variants in North America [PDF]

, 1999
Idhaliz Flores, Danuta Pieniążek, Nitza Morán, Angel Soler, Nayra Rodríguez, Margarita Alegrı́a, Mildred Vera, Luiz Mário Janini, Claudiu Bandea, Artur Ramos, Mark A. Rayfield, Yasuhiro Yamamura   +11 more
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Genetic variants in mRNA untranslated regions

Wiley Interdisciplinary Reviews - RNA, 2018
M. Steri, M. Idda, M. Whalen, V. Orrù
semanticscholar   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Identification of Genetic Variants in Status Epilepticus Associated With Fever. [PDF]

Brain Behav
Hanafusa H, Yamaguchi H, Morisada N, Ye MJ, Oikawa S, Tokumoto S, Nishiyama M, Nozu K, Nagase H.   +8 more
europepmc   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Two novel genetic variants in the WFDC2 gene from patients with bronchiectasis. [PDF]

Respir Res
Kim JM, Hwang S, Cho HW, Kim Y, Shin DM, Lee E, Kim M, Lee C, Kim JW, Park HY, Lee BH, Park MH.   +11 more
europepmc   +1 more source