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Genetic Variation of PPARs [PDF]

PPAR Research, 2009
Welcome to this special issue of PPAR Research dedicated to the “Genetic Variation of PPARs.” Since PPARs are nuclear transcription factors regulating multiple genes involved in energy production, glucose and lipid metabolism, polymorphisms in these receptors may influence the pathology of numerous diseases including obesity, diabetes, atherosclerosis,
Marie-Claude Vohl, Stefan Wieczorek, Mostafa Z. Badr   +2 more
openaire   +4 more sources

Genetic Variation and Atherosclerosis [PDF]

Current Genomics, 2008
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying the importance of inheritance in atherosclerosis are starting to be understood. Genetic variation, such as mutations or common polymorphisms has been shown to be involved in modulation of a range of risk ...
Biros, Erik, Karan, Mirko, Golledge, Jonathan   +2 more
openaire   +4 more sources

Cryptic genetic variation [PDF]

Current Biology, 2008
What is cryptic genetic variation? Cryptic genetic variation refers to unexpressed, bottled-up genetic potential. It is not normally seen, but is expressed under abnormal conditions such as in a new environment or a different genetic background.
Gibson Greg, Reed, Laura K.
openaire   +4 more sources

Genetic variation in the zebrafish [PDF]

Genome Research, 2006
Although zebrafish was introduced as a laboratory model organism several decades ago and now serves as a primary model for developmental biology, there is only limited data on its genetic variation. An establishment of a dense polymorphism map becomes a requirement for effective linkage analysis and cloning approaches in zebrafish. By comparing ESTs to
Guryev, Victor, Koudijs, Marco J., Berezikov, Eugene, Johnson, Stephen L., Plasterk, Ronald H.A., Van Eeden, Fredericus J.M., Cuppen, Edwin   +6 more
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Genetic Variation of Leafhopper, Nephotettix Virescens Distant Active Transmitters From Endemic and Non Endemic Areas of Rice Tungro Disease Based on RAPD Marker [PDF]

, 2014
Genetic variation of leafhopper, Nephotettix virescens Distant active transmitters from endemic and non endemic areas of rice tungro disease based on RAPD marker. Leafhopper, Nephotettix virescens Distant (Hemiptera: Cicadellidae) plays an important role
Supriyadi, S. (Supriyadi), Wijayanti, R. (Retno)   +1 more
core   +1 more source

Levels of genetic polymorphism: marker loci versus quantitative traits [PDF]

, 1998
Species are the units used to measure ecological diversity and alleles are the units of genetic diversity. Genetic variation within and among species has been documented most extensively using allozyme electrophoresis.
Butlin R. K., Butlin R. K., Meyer J., Muller H. J., Neems R. M., Nei M., Ward R. D., Watt W. B., Watt W. B., Wu C-I.   +9 more
core   +3 more sources

Phenotypic robustness can increase phenotypic variability after non-genetic perturbations in gene regulatory circuits [PDF]

, 2010
Non-genetic perturbations, such as environmental change or developmental noise, can induce novel phenotypes. If an induced phenotype confers a fitness advantage, selection may promote its genetic stabilization. Non-genetic perturbations can thus initiate
Ancel, Aubret, Azevedo, Bergman, Ciliberti, Ciliberti, Cooper, Davidson, de Jong, de Visser, Draghi, Draghi, Eldar, Elowitz, Espinosa-Soto, Espinosa-Soto, Ferrada, Fraser, Gibson, Gilbert, Gomez-Mestre, Griswold, Hall, Hermisson, Kim, Kimbrell, Kondrashov, Lande, Ledon-Rettig, Lehner, Levy, Lipman, Martin, Martin, Masel, Masel, Masel, McAdams, Meiklejohn, Moczek, Newman, Orr, Palmer, Palmer, Pigliucci, Pigliucci, Price, Proulx, Prud'homme, Raj, Rice, Roberts, Rodrigues, Rutherford, Schmalhausen, Schultes, Schuster, Shubin, Siegal, Snell-Rood, Sollars, Suzuki, Tirosh, van Nimwegen, Waddington, Waddington, Wagner, Wagner, Wagner, Wagner, Wagner, West-Eberhard, West-Eberhard, Wray   +73 more
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Benefits of host genetic diversity for resistance to infection depend on parasite diversity [PDF]

, 2010
Host populations with high genetic diversity are predicted to have lower levels of infection prevalence. This theory assumes that host genetic diversity results in variation in susceptibility and that parasites exhibit variation in infectivity. Empirical
Ebert, D., Ganz, H.
core   +1 more source

Cirsium species show disparity in patterns of genetic variation at their range-edge, despite similar patterns of reproduction and isolation [PDF]

, 2003
Genetic variation was assessed across the UK geographical range of Cirsium acaule and Cirsium heterophyllum. A decline in genetic diversity and increase in population divergence approaching the range edge of these species was predicted based on parallel ...
Alistair S. Jump, Ayre DJ, Ayres DR, Barrett SCH, Barton NH, Belkhir K, Bradshaw AD, Cain ML, Clapham AR, Comes HP, Eckert CG, Ellstrand NC, Ellstrand NC, F. Ian Woodward, Felsenstein J, Goudet J, Goudet J, Grime JP, Hamrick JL, Hedrick PW, Jump AS, McClintock KA, McLellan A, Moore RJ, Nei M, Oostermeijer GB, Pielou EC, Pigott CD, Pigott CD, Preston CD, Reinartz JA, Rice WR, Rogers HJ, Safriel UN, Schaal BA, Terry Burke, van Dorp D, Wang H, Weir BS, Widen B   +39 more
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Study on Genetic Variation and Relationships Among Four Acacia Species Using Rapd and Sscp Marker [PDF]

, 2010
Genetic diversity and relationship of four Acacia species, Acacia aulacocarpa, A. Cunn. ex Benth., A. auriculiformis Cunn. ex Benth., A. crassicarpa Cunn. ex Benth. and A. mangium Willd. were investigated using DNA molecular markers. Using RAPD analysis,
Shiraishi, S. (Susumu), Watanabe, A. (Atsushi), Widyatmoko, A. Y. (Anthonius)   +2 more
core   +1 more source