Results 1 to 10 of about 7,033,232 (294)

Disease-Associated Streptococcus pneumoniae Genetic Variation

Emerging Infectious Diseases
Streptococcus pneumoniae is an opportunistic pathogen that causes substantial illness and death among children worldwide. The genetic backgrounds of pneumococci that cause infection versus asymptomatic carriage vary substantially.
Shimin Yang, Jianyu Chen, Jinjian Fu, Jiayin Huang, Ting Li, Zhenjiang Yao, Xiaohua Ye   +6 more
doaj   +1 more source

Natural genetic variation in MIR172 isolated from Brassica species

Biologia Plantarum, 2014
The present study reports a natural variation in microRNA172 (MIR172) family members isolated from six species of genus Brassica. The analysis of nucleotide polymorphism across 44 Brassica MIR172 homologs revealed a higher conservation in the predicted ...
S. M. Shivaraj, P. Dhakate, P. Mayee, M. S. Negi, A. Singh   +4 more
doaj   +1 more source

Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery

Nature Genetics, 2016
The Greater Middle East (GME) has been a central hub of human migration and population admixture. The tradition of consanguinity, variably practiced in the Persian Gulf region, North Africa, and Central Asia, has resulted in an elevated burden of ...
Eric M. Scott, Anason S. Halees, Y. Itan, E. Spencer, Yupeng He, Mostafa A. Azab, S. Gabriel, Aziz Belkadi, B. Boisson, L. Abel, A. Clark, F. Alkuraya, J. Casanova, J. Gleeson   +13 more
semanticscholar   +1 more source

Genetic variation among 82 pharmacogenes: The PGRNseq data from the eMERGE network

Clinical pharmacology and therapy, 2016
Genetic variation can affect drug response in multiple ways, although it remains unclear how rare genetic variants affect drug response. The electronic Medical Records and Genomics (eMERGE) Network, collaborating with the Pharmacogenomics Research ...
W. Bush, D. Crosslin, A. Owusu-Obeng, John M. Wallace, B. Almoguera, Melissa A. Basford, S. Bielinski, David Carrell, John J. Connolly, D. Crawford, K. Doheny, Carlos J Gallego, A. Gordon, B. Keating, Jacqueline Kirby, Terrie E. Kitchner, S. Manzi, A. Mejía, Vivian Pan, Cassandra L. Perry, J. Peterson, C. Prows, J. Ralston, S. Scott, Aaron Scrol, Maureen E. Smith, S. Stallings, T. Veldhuizen, Wendy A. Wolf, S. Volpi, Ken Wiley, Rongling Li, T. Manolio, Erwin Bottinger, M. Brilliant, D. Carey, R. L. Chisholm, C. Chute, J. Haines, H. Hakonarson, J. Harley, I. Holm, I. Kullo, G. Jarvik, E. Larson, C. McCarty, M. Williams, J. Denny, L. Rasmussen-Torvik, D. Roden, M. Ritchie   +50 more
semanticscholar   +1 more source

A general framework for estimating the relative pathogenicity of human genetic variants

Nature Genetics, 2014
Current methods for annotating and interpreting human genetic variation tend to exploit a single information type (for example, conservation) and/or are restricted in scope (for example, to missense changes).
Martin Kircher, D. Witten, Preti Jain, B. O’Roak, G. Cooper, J. Shendure   +5 more
semanticscholar   +1 more source

Divergência genética entre variedades de videiras do Banco Ativo de Germoplasma da Embrapa Semiárido

Revista Ciência Agronômica
RESUMOEste trabalho teve por objetivo avaliar a divergência genética entre 31 variedades de videira do Banco de Germoplasma da Embrapa Semiárido, considerando características de qualidade, compostos de importância funcional e atividade antioxidante dos ...
Patrício Ferreira Batista, Maria Auxiliadora Coêlho de Lima, Patrícia Coelho de Souza Leão, Flávio de França Souza, Ricardo Elesbão Alves   +4 more
doaj   +1 more source

Temperature is a cryptic factor shaping the geographical pattern of genetic variation in Ceratophyllum demersum across a subtropical freshwater lake

Plant Diversity
Macrophyte habitats exhibit remarkable heterogeneity, encompassing the spatial variation of abiotic and biotic components such as changes in water conditions and weather as well as anthropogenic stressors.
Yixian Li, Xuyao Zhao, Manli Xia, Xinzeng Wei, Hongwei Hou   +4 more
doaj   +1 more source

Genetic variation in human apolipoprotein E

Journal of Lipid Research, 1982
Genetic variation in human apoprotein E was studied using the technique of isoelectric focusing applied to delipidated very low density lipoprotein from 426 Christchurch blood donors and 7 patients with type III hyperlipoproteinemia.
M R Wardell, P A Suckling, E D Janus
doaj   +1 more source

Genetic variability in the Skyros pony and its relationship with other Greek and foreign horse breeds

Genetics and Molecular Biology, 2011
In Greece, seven native horse breeds have been identified so far. Among these, the Skyros pony is outstanding through having a distinct phenotype. In the present study, the aim was to assess genetic diversity in this breed, by using different types of ...
Elisabeth Bömcke, Nicolas Gengler, E. Gus Cothran   +2 more
doaj  

Genetic structure and phenotypic variation in wild populations of the medicinal tetraploid species Bromelia antiacantha (Bromeliaceae) [PDF]

, 2011
Camila Martini Zanella, Manuela Bruxel, Gecele Matos Paggi, Márcia Goetze, Miriam Valli Büttow, Fernanda Witt Cidade, Fernanda Bered   +6 more
openalex   +1 more source