Results 191 to 200 of about 634,337 (325)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Genetic surveillance of insecticide resistance in African Anopheles populations to inform malaria vector control [PDF]

Penelope A. Hancock, Eric Ochomo, Louisa A. Messenger   +2 more
openalex   +1 more source

In vivo evaluation of an EIAV vector for the systemic genetic delivery of therapeutic antibodies [PDF]

, 2005
Abigail Lamikanra, Kevin A. Myers, N.P. Ferris, Kyriacos Mitrophanous, Miles W. Carroll   +4 more
openalex   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Generalists or Specialists? Testing Genetic Specificity of <i>Leucocytozoon</i> Lineages and Black Fly Vectors in Thailand. [PDF]

Biology (Basel)
Jumpato W, Wannasingha W, Sakundet K, Jaroenchaiwattanachote C, Thanchomnang T, Maleewong W, Adler PH, Pramual P.   +7 more
europepmc   +1 more source

A strength-biased prediction model for forecasting exchange rates using support vector machines and genetic algorithms

, 2016
Mustafa Onur Özorhan, İsmail Hakkı Toroslu, Onur T. Şehitoğlu   +2 more
openalex   +2 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Carbon nanotube and carbon dot mediated plasmid DNA delivery in cowpea leaves. [PDF]

PLoS One
Saglam M, Tsakirpaloglou N, Bridgeland A, Miller R, Thomson MJ, Septiningsih EM.   +5 more
europepmc   +1 more source

Volatility Modelling and Prediction by Hybrid Support Vector Regression with Chaotic Genetic Algorithms

, 2014
Phichhang Ou, Hengshan Wang
openalex   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source