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Genetic manipulation of insect vectors as a strategy for the control of vector-borne disease
Annals of Tropical Medicine & Parasitology, 1994A variety of very effective methods have been employed for suppressing insect vector populations, including the application of biological control agents and the elimination of breeding sites, with a continuing and heavy reliance on the use of chemical insecticides.
J M, Crampton +5 more
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Herpesviruses as Genetic Vectors
1995The members of the Herpesviridae family are large, DNA-containing, enveloped viruses. Nearly 100 herpesviruses infect a broad spectrum of the animal kingdom (Roizman 1990). So far, seven different types of human herpesviruses have been described (Table 5.1).
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Genetic manipulation of endothelial cells by viral vectors
Thrombosis and Haemostasis, 2009SummaryThe need for uncovering molecular mechanisms in endothelial cell biology has tremendously increased in the last decades as it became more and more clear that the endothelium is an important target in nearly all diseases and treatments (drug delivery) and plays a central role in regeneration processes.
Dirk, Lindemann, Hans, Schnittler
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Vector quantizer design using genetic algorithms
Proceedings of Data Compression Conference - DCC '96, 2002The design of vector quantizers (VQs) that yield minimal distortion is one of the most challenging problems in source coding. The problem of VQ design is to find a codebook that gives the least overall distortion (or equivalently, the largest signal-to-noise ratio (SNR)) for a given set of input vectors.
Sunghyun Choi 0001, Wee Keong Ng
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The biogeography and population genetics of neotropical vector species
Heredity, 2007Phylogenetic and population genetic data support the Pliocene or Pleistocene divergences of the co-distributed hematophagous insect vectors, the sand fly Lutzomyia longipalpis s.l., the mosquitoes Anopheles darlingi and A. albitarsis s.l., and the triatomines Rhodnius prolixus and R. robustus.
J E, Conn, L, Mirabello
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HSV-1 Amplicon Vectors as Genetic Vaccines
2019HSV-1 amplicon vectors have been used as platforms for the generation of genetic vaccines against both DNA and RNA viruses. Mice vaccinated with such vectors encoding structural proteins from both foot-and-mouth disease virus and rotavirus were partially protected from challenge with wild-type virus (D'Antuono et al., Vaccine 28:7363-7372, 2010 ...
Anita F, Meier, Andrea S, Laimbacher
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Plasmid RP4 as a vector replicon in genetic engineering
Nature, 1975THERE is now considerable interest in the construction of plasmids containing DNA fragments from a variety of bacterial genera, for purposes of studying the expression of the genetic potentialities of the incorporated bacterial DNA in different bacterial hosts.
A E, Jacob, N J, Grinter
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Genetic Modification of Chondrocytes Using Viral Vectors
2010The use of isolated cells to construct engineered tissues provides the opportunity to genetically modify those cells prior to the formation of tissue. This should make it possible to create transgenic human model tissues that can be used to determine gene function as well as to identify or validate potential therapeutic targets.
Teresa, Coughlan +3 more
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Entrapment Vectors: A New Tool for Mammalian Genetics
Nature Biotechnology, 1990The use of mouse embryonic stem (ES) cells has facilitated the creation of mouse strains carrying desired genetic alterations. Recently, "entrapment" vectors have been developed to identify and mutate genes active during embryogenesis. These vectors in combination with ES cells may provide an efficient screening strategy to find genes that control ...
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Vector Genetics in Malaria Control
2006Anopheles culicifacies is the major vector of rural malaria in the plains of India. Cytogenetic analysis of polytene chromosomes revealed that A. culicifacies is a complex of five sibling species designated as A, B, C, D, and E. Each sibling species has its own distribution pattern which is influenced by the environment. Sibling species differ in their
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