Results 121 to 130 of about 1,455,121 (302)
, 2010 This OER consists of an instructional sheet produced by GENIE CETL in the Department of Genetics. By the end of this material you would have learnt about: The way in which genes control the growth and development of an organism throughout its life ...
GENIE CETL
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Behavioral Genetics in the Courtrooms [PDF]
, 2012 The paper posits the thesis that there is no methodological shortcut between behavioral genetics and legal sciences, and we are not into position to walk on the bridge between genetics and law (especially, in the courtrooms).
Zyzik, Radosław
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Systems genetics of lifespan and senescence in Drosophila melanogaster
BMC BiologyBackground As populations age, the number of people with age-related chronic diseases increases, causing significant social, economic and health problems.
Maryam Nasiri Aghdam +9 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
, 2013 application/pdf; Includes bibliographical references (page [44 of 71]).A set of 9 Annual Reports from Subcommittees of the Governor's Behavioral Health Services Planning Council, and 1 summary.Aging Subcommittee Report 2013 (July 10, 2013).
Kansas. Governor's Behavioral Health Services Planning Council.
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source