Results 221 to 230 of about 1,219,858 (356)

Elastic Deformation of Cellulose/Lignin‐Based Anode for Rejuvenating Aged Mix‐Cultured Electroactive Biofilms

open access: yesAdvanced Science, EarlyView.
A new strategy for revitalizing aged biofilms using the elastic deformation of biomass‐based flexible carbon aerogel is proposed. The elastic deformation removes the nonelectrogenic bacteria and the dead electrogenic bacteria, as well as a lot of loosely bound extracellular polymer materials.
Xue Liu   +15 more
wiley   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

open access: yesAdvanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang   +5 more
wiley   +1 more source

Microbial diversity of high-elevated fumarole fields, low-biomass communities on the boundary between ice and fire. [PDF]

open access: yesSci Rep
Shevchenko AY   +8 more
europepmc   +1 more source

A Phase‐Separated SR Protein Reprograms Host Pre‐mRNA Splicing to Enhance Disease Susceptibility

open access: yesAdvanced Science, EarlyView.
This study identifies SR30, a splicing factor, as a negative regulator of tomato immunity. During Phytophthora infestans infection, the elevated SR30 forms nuclear condensates to suppress the alternative splicing (AS) of defense‐related genes in a phase separation manner.
Dong Yan   +11 more
wiley   +1 more source

Systems genetics uncovers associations among host amylase locus, gut microbiome, and metabolic traits in mice. [PDF]

open access: yesMicrobiome
Zhang Q   +7 more
europepmc   +1 more source

A Bio‐Responsive Hydrogel with Spatially Heterogeneous Structure for Treating Infectious Tissue Injuries

open access: yesAdvanced Science, EarlyView.
The hydrogel incorporates Ag⁺‐loaded Preyssler‐type polyoxometalates (POMs) that release Ag⁺ ions in response to endogenous Na⁺ ions, ensuring controlled antibacterial activity. The spatially heterogeneous structure, created through dual‐channel fiber stacking and in situ cross‐linking, enhances structural integrity and promotes tissue regeneration ...
Zongtai Li   +9 more
wiley   +1 more source

Molecular Mechanisms and Emerging Precision Therapeutics in the Gut Microbiota-Cardiovascular Axis. [PDF]

open access: yesCureus
Ponce Alencastro JA   +5 more
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

open access: yesAdvanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua   +19 more
wiley   +1 more source

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