Advanced Science, EarlyView.ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo +13 more
wiley +1 more source
The microbiota-gut-brain-epigenome axis as a novel therapeutic target for decoding postpartum depression. [PDF]
Front Med (Lausanne)Zheng B, Shen X, Han N, Guo X, Wan S.
europepmc +1 more source
Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects
Advanced Science, EarlyView.Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang +9 more
wiley +1 more source
Editorial: Genetics and genomics of emerging and multifactorial stresses affecting plant survival and associated plant microbiomes. [PDF]
Front Plant SciPunnuri SM, Thudi M, Mir RR.
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Advanced Science, EarlyView.Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
Cosmetic Interventions for Skin Microbiome Modulation: Current Strategies and Future Directions. [PDF]
Skin Res TechnolTaléns-Visconti R +2 more
europepmc +1 more source
Advanced Science, EarlyView.This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
Nearly a century of discoveries in bacterial genetics and their continuing impact on the field. [PDF]
GeneticsBaltrus DA, Merrikh H, Uecker H, Wong A.
europepmc +2 more sources
Correction for Ferreira and Rediers, "Draft genome sequences of 25 candidate biocontrol bacteria against <i>Phytophthora cactorum</i>". [PDF]
Microbiol Resour AnnouncFerreira J, Rediers H.
europepmc +1 more source
Advanced Science, EarlyView.The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty +21 more
wiley +1 more source