Results 141 to 150 of about 2,225,252 (353)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Moran model of population genetics : case studies with recombination and selection [PDF]

open access: yes, 2012
Hustedt T. The Moran model of population genetics : case studies with recombination and selection. Bielefeld: Universität Bielefeld; 2012.The Moran model is a widespread model for a finite population in the field of population genetics.
Hustedt, Thiemo
core  

MEGA2: molecular evolutionary genetics analysis software

open access: yesBioinform., 2001
Sudhir Kumar   +3 more
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

THE INFLUENCE OF GENETICS ON CONTEMPORARY THINKING

open access: yes, 2007
Preface -- Overview of contents -- An historical outline and further reading -- Acknowledgements -- List of contributors -- Interview of François Jacob (FJ) by Anne Fagot-Largeault (AFL) -- Entretien de François Jacob (FJ) avec Anne Fagot-Largeault

core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Genetics and Antisocial Behavior: Substance versus Sound Bytes

open access: yes, 1996
Symposium: Genetics and ...
Carey, Gregory, Gottesman, Irving I.
core  

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