Results 301 to 310 of about 2,771,911 (398)

Deciphering the phenotypic spectrum associated with MIA3-related odontochondrodysplasia. [PDF]

J Hum Genet
Abdel-Hamid MS, Elhossini RM, Abdel-Ghafar SF, Mehrez M, Aglan MS, Hassib NF.   +5 more
europepmc   +1 more source

THE GENETICS OF RETINOBLASTOMA

, 1944
A D Griffith, Arnold Sorsby
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Allele ages provide limited information about the strength of negative selection. [PDF]

Genetics
Shastry V, Berg JJ.
europepmc   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Publisher Correction: Genetic diversity and origin of Kazakh Tobet Dogs. [PDF]

Sci Rep
Perfilyeva A, Bespalova K, Kuzovleva Y, Mussabayev R, Begmanova M, Amirgalyeva A, Vishnyakova O, Nazarenko I, Zhaxsylykova A, Yerzhan A, Perfilyeva Y, Dzhaembaeva T, Khamchukova A, Plakhov K, Torekhanov A, Djansugurova L, Zhunussova G, Bekmanov B.   +17 more
europepmc   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Ecological genomics beyond genome reports. [PDF]

G3 (Bethesda)
Verhoeven KJF, Pyhäjärvi T.
europepmc   +1 more source

On the Specificity of the Response of Mouse Epidermis to Vitamin A11From the Department of Zoology and its Cancer Research Genetics Laboratory, University of California, Berkeley, California.

, 1958
Donald J. Lawrence, Howard A. Bern
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source