Results 301 to 310 of about 2,225,252 (353)
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Genetic counselling and the new genetics
Trends in Genetics, 1988Abstract The mapping of most important human disease genes has already been accomplished, promising epochal changes in health care and disease prevention. This article explores the potential benefits and dangers, emphasizing the high priority that must be given to non-directive genetic counselling.
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Seminars in Cerebrovascular Diseases and Stroke, 2002
Computed tomography and magnetic resonance imaging of the brains of elderly individuals frequently show areas of altered signal intensity in the periventricular and subcortical white matter, referred to as leukoaraiosis. Although mildly affected individuals appear asymptomatic, larger burdens of leukoaraiosis are associated with deficits of cognition ...
Stephen T, Turner, Myriam, Fornage
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Computed tomography and magnetic resonance imaging of the brains of elderly individuals frequently show areas of altered signal intensity in the periventricular and subcortical white matter, referred to as leukoaraiosis. Although mildly affected individuals appear asymptomatic, larger burdens of leukoaraiosis are associated with deficits of cognition ...
Stephen T, Turner, Myriam, Fornage
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Calcified Tissue International, 1994
Osteoporosis (OP) is the most prevalent metabolic bone disease among developed countries and it is defined as a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to nontraumatic fracture [1].
BRANDI, MARIA LUISA +7 more
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Osteoporosis (OP) is the most prevalent metabolic bone disease among developed countries and it is defined as a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to nontraumatic fracture [1].
BRANDI, MARIA LUISA +7 more
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Genetic imprinting in clinical genetics
Development, 1990ABSTRACT Genetic, and indeed genomic, imprinting does occur in humans. This is manifest at the level of the genome, the individual chromosome, subchromosomal region or fragile site, or the single locus. The best evidence at the single gene level comes from a consideration of familial tumour syndromes.
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1997
Publisher Summary The genetic analysis of apoptosis, or programmed cell death, provides important information on the biology of naturally occurring cell death. Identification of genes regulating apoptosis has confirmed that this process follows a similar paradigm in all multicellular organisms.
Desnoyers, S, Hengartner, M O
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Publisher Summary The genetic analysis of apoptosis, or programmed cell death, provides important information on the biology of naturally occurring cell death. Identification of genes regulating apoptosis has confirmed that this process follows a similar paradigm in all multicellular organisms.
Desnoyers, S, Hengartner, M O
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Large-scale integration of the plasma proteome with genetics and disease
Nature Genetics, 2021E. Ferkingstad +39 more
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Genetic and Non-Genetic Operators in ALECSYS
Evolutionary Computation, 1993It is well known that standard learning classifier systems, when applied to many different domains, exhibit a number of problems: payoff oscillation, difficulty in regulating interplay between the reward system and the background genetic algorithm (GA), rule chains' instability, default hierarchies' instability, among others.
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The Lancet, 2004
The review first summarizes the molecular biology methods used in forensic genetics in Denmark. In criminal cases, there is international consensus about investigation of Short Tandem Repeat (STR)-regions with polymerase chain reaction (PCR)based methods that are standardised through international collaboration.
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The review first summarizes the molecular biology methods used in forensic genetics in Denmark. In criminal cases, there is international consensus about investigation of Short Tandem Repeat (STR)-regions with polymerase chain reaction (PCR)based methods that are standardised through international collaboration.
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1998
The Mendelian analysis of genetic variation, available as induced mutants or as natural variation, requires a number of steps that are described in this chapter. These include the determination of the number of genes involved in the observed trait's variation, the determination of dominance relationships between alleles of the same locus, and epistatic
Koornneef, M. +2 more
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The Mendelian analysis of genetic variation, available as induced mutants or as natural variation, requires a number of steps that are described in this chapter. These include the determination of the number of genes involved in the observed trait's variation, the determination of dominance relationships between alleles of the same locus, and epistatic
Koornneef, M. +2 more
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Child and Adolescent Psychiatric Clinics of North America, 1998
In summary, autism genetics has moved from a time of identification of heritability and determination of risk of "lesser variants" or the "broader phenotype" in relatives to a phase where some cases of autism have a definite basis such as maternally inherited duplications of 15q11-q13, identification of mutations causing AS, Rett syndrome, and FRAXA ...
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In summary, autism genetics has moved from a time of identification of heritability and determination of risk of "lesser variants" or the "broader phenotype" in relatives to a phase where some cases of autism have a definite basis such as maternally inherited duplications of 15q11-q13, identification of mutations causing AS, Rett syndrome, and FRAXA ...
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