Results 71 to 80 of about 2,771,911 (398)
Fluctuations of fitness distributions and the rate of Muller's ratchet [PDF]
, 2012 The accumulation of deleterious mutations is driven by rare fluctuations which lead to the loss of all mutation free individuals, a process known as Muller's ratchet.
Boris I. Shraiman +12 more
core +2 more sources
Population Ecology, EarlyView.In this study, we compared three methods for kinship identification using different algorithms in samples of wild Pacific bluefin tuna and generated genotyping data. The three methods resulted in different numbers of inferred kinship pairs for both generated and actual data. Particularly for the half‐sibling pairs, considerable number of false‐positive
Yohei Tsukahara +5 more
wiley +1 more source
Genetic Samples and Genetic Philanthropy
AMA Journal of Ethics, 2004 Genetic research is threatened by lack of samples, and public policy should be developed to encourage public participation. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
Gary E. Marchant, Michael E. Berens
openaire +3 more sources
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
Genetic ties and genetic mixups [PDF]
Journal of Medical Ethics, 2003 In a recent case in Great Britain, a couple described as “white” underwent in vitro fertilisation and gave birth to twins described as “black”. In the sense of a fair adjudication of this particular case, serving justice requires a thick description and a sensitive understanding of the relevant facts.
T H Murray, G E Kaebnick
openaire +2 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Arlequin (version 3.0): An integrated software package for population genetics data analysis
Evolutionary bioinformatics online, 2005 Arlequin ver 3.0 is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of ...
L. Excoffier +2 more
semanticscholar +1 more source
, 2014 The concept of positional information is central to our understanding of how cells in a multicellular structure determine their developmental fates.
Dubuis, Julien O +3 more
core +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Genetics of 35 blood and urine biomarkers in the UK Biobank
Nature Genetics, 2020 Clinical laboratory tests are a critical component of the continuum of care. We evaluate the genetic basis of 35 blood and urine laboratory measurements in the UK Biobank (n = 363,228 individuals).
Nasa Sinnott-Armstrong +19 more
semanticscholar +1 more source